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Testing Data (Peptide-+)

DUSP9 Antibody | anti-DUSP9 antibody

DUSP9 Antibody

Gene Names
DUSP9; MKP4; MKP-4
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DUSP9; DUSP9 Antibody; Dual specificity protein phosphatase 9; EC 3.1.3.48; EC 3.1.3.16; Mitogen-activated protein kinase phosphatase 4; MAP kinase phosphatase 4; MKP-4; MKP4; anti-DUSP9 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
DUSP9 antibody detects endogenous levels of total DUSP9 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
384
Applicable Applications for anti-DUSP9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DUSP9.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using DUSP9 antibody. Western blot analysis of extracts from HeLa cells, using DUSP9 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using DUSP9 antibody. Western blot analysis of extracts from HeLa cells, using DUSP9 antibody.)

Immunofluorescence (IF)

(Peptide-+ Immunofluorescence analysis of HeLa cells, using DUSP9 antibody.)

Immunofluorescence (IF) (Peptide-+ Immunofluorescence analysis of HeLa cells, using DUSP9 antibody.)
References
Muda M., J. Biol. Chem. 272:5141-5151(1997). Ross M.T., Nature 434:325-337(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,868 Da
NCBI Official Full Name
dual specificity protein phosphatase 9
NCBI Official Synonym Full Names
dual specificity phosphatase 9
NCBI Official Symbol
DUSP9
NCBI Official Synonym Symbols
MKP4; MKP-4
NCBI Protein Information
dual specificity protein phosphatase 9
UniProt Protein Name
Dual specificity protein phosphatase 9
UniProt Gene Name
DUSP9
UniProt Synonym Gene Names
MKP4; MAP kinase phosphatase 4; MKP-4

NCBI Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Uniprot Description

Inactivates MAP kinases. Has a specificity for the ERK family.

Research Articles on DUSP9

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Product Notes

The DUSP9 dusp9 (Catalog #AAA855620) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The DUSP9 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DUSP9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the DUSP9 dusp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUSP9, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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