Typical Testing Data/Standard Curve (for reference only)
Human Thyroid Hormone Receptor Alpha (THRa) ELISA Kit | THRa elisa kit
Human Thyroid Hormone Receptor Alpha (THRa) ELISA Kit
No significant cross-reactivity or interference between Thyroid Hormone Receptor Alpha (THRa) and analogues was observed.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
TR-alpha: nuclear hormone receptor and transcription factor. High affinity receptor for triiodothyronine. Interacts with SRC-3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Four splice variant isoforms have been described.
Protein type: Nuclear receptor; DNA-binding; Transcription factor
Cellular Component: mitochondrion; cytoplasm; cytosol; nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein dimerization activity; protein domain specific binding; ligand-dependent nuclear receptor activity; protein homodimerization activity; zinc ion binding; chromatin DNA binding; metal ion binding; transcription factor binding; protein binding; single-stranded RNA binding; DNA binding; TATA-binding protein binding; sequence-specific DNA binding; protein heterodimerization activity; protein complex binding; steroid hormone receptor activity; thyroid hormone receptor activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcriptional preinitiation complex assembly; cytoplasmic sequestering of transcription factor; ossification; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; hormone-mediated signaling; negative regulation of transcription factor activity; positive regulation of female receptivity; regulation of myeloid cell apoptosis; regulation of lipid catabolic process; regulation of heart contraction; regulation of transcription from RNA polymerase II promoter; organ morphogenesis; female courtship behavior; learning and/or memory; regulation of transcription, DNA-dependent; thyroid gland development; erythrocyte differentiation; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; response to cold; negative regulation of transcription, DNA-dependent; cartilage condensation
Research Articles on THRa
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Product Notes
The Human THRa thra (Catalog #AAA2023108) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2023108 ELISA Kit recognizes Human THRa. It is sometimes possible for the material contained within the vial of "Thyroid Hormone Receptor Alpha (THRa), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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