Typical Testing Data/Standard Curve (for reference only)
Mouse Thyroid hormone receptor alpha ELISA Kit | Thra elisa kit
Mouse Thyroid hormone receptor alpha ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is one of several nuclear hormone receptors that bind thyroid hormones such as triiodothyronine and thyroxine with high affinity. The encoded protein is a transcription factor that can activate or repress transcription. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2015]
Uniprot Description
TR-alpha: nuclear hormone receptor and transcription factor. High affinity receptor for triiodothyronine. Interacts with SRC-3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Four splice variant isoforms have been described.
Protein type: DNA-binding; Nuclear receptor; Transcription factor
Cellular Component: cytoplasm; cytosol; mitochondrion; nucleus
Molecular Function: chromatin DNA binding; DNA binding; ligand-dependent nuclear receptor activity; metal ion binding; protein binding; protein complex binding; protein dimerization activity; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; single-stranded RNA binding; steroid hormone receptor activity; TATA-binding protein binding; thyroid hormone receptor activity; transcription factor activity; transcription factor binding; zinc ion binding
Biological Process: cartilage condensation; cytoplasmic sequestering of transcription factor; erythrocyte differentiation; female courtship behavior; hormone-mediated signaling; intracellular receptor-mediated signaling pathway; learning and/or memory; negative regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; negative regulation of transcriptional preinitiation complex assembly; organ morphogenesis; ossification; positive regulation of female receptivity; positive regulation of transcription from RNA polymerase II promoter; regulation of heart contraction; regulation of lipid catabolic process; regulation of myeloid cell apoptosis; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to cold; steroid hormone mediated signaling; thyroid gland development; transcription from RNA polymerase II promoter; transcription, DNA-dependent
Research Articles on Thra
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Product Notes
The Mouse Thra thra (Catalog #AAA2881958) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881958 ELISA Kit recognizes Mouse Thra. It is sometimes possible for the material contained within the vial of "Thyroid hormone receptor alpha, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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