Human B7-H4 ELISA Kit | B7-H4 elisa kit

Human B7-H4 ELISA Kit

Cat. Num. AAA3803908

• Gene Names: Vtcn1; B7x; B7h4; B7s1; BC032925
• Reactivity: Human
• Synonyms: B7-H4; Human B7-H4 ELISA Kit; B7-H4 elisa kit

• Reactivity: Human
• Sequence Length: 283

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 62.5ng/ml-1000ng/ml
• Sensitivity: 1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for B7-H4 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofB7-H4in the sample, This B7-H4ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusB7-H4concentration. The concentration ofB7-H4in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 81912664
• NCBI GeneID: 242122
• UniProt Accession #: Q7TSP5
• NCBI Official Full Name: V-set domain containing T-cell activation inhibitor 1
• NCBI Official Synonym Full Names: V-set domain containing T cell activation inhibitor 1
• NCBI Official Symbol: Vtcn1
• NCBI Official Synonym Symbols: B7x; B7h4; B7s1; BC032925
• NCBI Protein Information: V-set domain containing T-cell activation inhibitor 1
• UniProt Protein Name: V-set domain containing T-cell activation inhibitor 1
• UniProt Gene Name: Vtcn1
• UniProt Synonym Gene Names: B7-H4

Uniprot Description

VTCN1: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3|3 F2.2

Cellular Component: external side of plasma membrane

Molecular Function: receptor binding

Biological Process: negative regulation of T cell activation; positive regulation of T cell proliferation; response to protozoan