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Western Blot (WB) (Fig-1: Western blot analysis of B7-H4, mouse. Anti-B7-H4, mouse antibody (11-7575) was used at 2 ug/ml on (1) EL-4 and 0.5 ug/ml on (2) Recombinant lysates.)

Rabbit anti-Mouse B7-H4 Polyclonal Antibody | anti-B7-H4 antibody

Polyclonal Antibody to B7-H4 mouse

Gene Names
Vtcn1; B7x; B7h4; B7s1; BC032925
Reactivity
Mouse
Applications
Western Blot
Purity
Purified
Protein A Chromatography
Synonyms
B7-H4; Polyclonal Antibody; Polyclonal Antibody to B7-H4 mouse; Vtcn1; V-set domain containing T-cell activation inhibitor 1; B7 homolog 4; Immune costimulatory protein B7-H4; Protein B7S1; T cell costimulatory molecule B7x; anti-B7-H4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified
Protein A Chromatography
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Sequence Length
283
Applicable Applications for anti-B7-H4 antibody
Western Blot (WB)
Application Notes
WB: 0.5-2 ug/ml
Immunogen Information
A partial length recombinant B7-H4 mouse protein (amino acids 50-270) was used as the immunogen for this antibody.
Antigen
B7-H4 mouse
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.

Western Blot (WB)

(Fig-1: Western blot analysis of B7-H4, mouse. Anti-B7-H4, mouse antibody (11-7575) was used at 2 ug/ml on (1) EL-4 and 0.5 ug/ml on (2) Recombinant lysates.)

Western Blot (WB) (Fig-1: Western blot analysis of B7-H4, mouse. Anti-B7-H4, mouse antibody (11-7575) was used at 2 ug/ml on (1) EL-4 and 0.5 ug/ml on (2) Recombinant lysates.)
Product Categories/Family for anti-B7-H4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
30,875 Da
NCBI Official Full Name
V-set domain containing T-cell activation inhibitor 1
NCBI Official Synonym Full Names
V-set domain containing T cell activation inhibitor 1
NCBI Official Symbol
Vtcn1
NCBI Official Synonym Symbols
B7x; B7h4; B7s1; BC032925
NCBI Protein Information
V-set domain containing T-cell activation inhibitor 1
UniProt Protein Name
V-set domain containing T-cell activation inhibitor 1
UniProt Gene Name
Vtcn1
UniProt Synonym Gene Names
B7-H4

Uniprot Description

VTCN1: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3|3 F2.2

Cellular Component: external side of plasma membrane

Molecular Function: receptor binding

Biological Process: negative regulation of T cell activation; positive regulation of T cell proliferation; response to protozoan

Research Articles on B7-H4

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Product Notes

The B7-H4 vtcn1 (Catalog #AAA668518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to B7-H4 mouse reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's B7-H4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-2 ug/ml. Researchers should empirically determine the suitability of the B7-H4 vtcn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B7-H4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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