Typical Testing Data/Standard Curve (for reference only)

Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit | SRD5A1 elisa kit

Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit

Gene Names

Srd5a1; S5AR 1

Reactivity

Human

Synonyms

3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1); Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit; SRD5A1 elisa kit

Ordering
Cat. Num. AAA9716516 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Human

Sequence Length

255

Assay Type

Sandwich

Preparation and Storage

Store at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for SRD5A1 elisa kit

Principle of the Assay: Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit employs a two-site sandwich ELISA to quantitate SRD5A1 in samples. An antibody specific for SRD5A1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SRD5A1 present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human SRD5A1 detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of SRD5A1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Background/Introduction: SRD5A1 (Steroid 5 Alpha-Reductase 1) is a Protein Coding gene. Diseases associated with SRD5A1 include Prostatic Hyperplasia, Benign and 5-Alpha Reductase Deficiency. Among its related pathways are Metabolism and superpathway of steroid hormone biosynthesis. Steroid 5-alpha-reductase catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT).

NCBI and Uniprot Product Information

NCBI GI #

77404421

NCBI GeneID

24950

NCBI Accession #

NCBI GenBank Nucleotide #

NP_058766.2

UniProt Accession #

P24008

NCBI Official Full Name

3-oxo-5-alpha-steroid 4-dehydrogenase 1

NCBI Official Synonym Full Names

steroid 5 alpha-reductase 1

NCBI Official Symbol

Srd5a1

NCBI Official Synonym Symbols

S5AR 1

NCBI Protein Information

3-oxo-5-alpha-steroid 4-dehydrogenase 1

UniProt Protein Name

3-oxo-5-alpha-steroid 4-dehydrogenase 1

Protein Family

3-oxo-5-alpha-steroid 4-dehydrogenase

UniProt Gene Name

Srd5a1

UniProt Synonym Gene Names

S5AR 1

NCBI Description

catalyzes the conversion of testosterone to dihydrotestosterone; required for male sex differentiation [RGD, Feb 2006]

Uniprot Description

Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

Research Articles on SRD5A1

1. Ziram inhibited SRD5A1 and AKR1C14 activities, thus possibly interfering with neurosteroid production in rats.

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Product Notes

The Human SRD5A1 srd5a1 (Catalog #AAA9716516) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716516 ELISA Kit recognizes Human SRD5A1. It is sometimes possible for the material contained within the vial of "3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) ELISA Kit | SRD5A1 elisa kit