FGF3 recombinant protein

FGF3

Cat. Num. AAA516999

• Gene Names: FGF3; INT2; HBGF-3
• Applications: Cell Assay
• Synonyms: FGF3; HBGF-3; Proto-oncogene Int-2; Heparin-binding growth factor 3; FGF3 recombinant protein

• Host: E Coli
• Form/Format: Lyophilized from a 0.2 um filtered solution in PBS, DTT and EDTA.

• Applicable Applications for FGF3 recombinant protein: Cell Assay
• Species: Human
• Endotoxin Level: <1.0EU/ug of recombinant protein as determined by the LAL method
• Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1mg/ml. This solution can then be diluted into other buffers.
• Preparation and Storage: The lyophilized protein is stable for at least one year from date of receipt at -70 degree C. Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree -8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Activity

(Sample Cell Assay Data: The ED50 as determined by the dose-dependent stimulation of mouse fibroblasts was )

SDS-Page

(Purity: Recombinant Human FGF3 resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.)

Related Product Information for FGF3 recombinant protein

Recombinant Human FGF3 was expressed in E Coli cells. The protein accession number is P11487
FGF3 belongs to the FGF family, members of which act on cells of mesodermal and neuroectodermal origin. Originally designated int2, the FGF3 gene was initially identified as a protooncogene in mice. FGF3 plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation and is required for normal ear development. Heparan sulfate glycosaminoglycans function as co-receptors to increase the affinity between FGF3 and its receptors; FGFR1 and FGFR2. Human and mouse FGF3 are known to share 88% amino acid sequence identity. Recombinant Human FGF3 is a single polypeptide of 21kDa.

Product Categories/Family for FGF3 recombinant protein

Growth Factors

NCBI and Uniprot Product Information

• NCBI GI #: 4885233
• NCBI GeneID: 2248
• NCBI Accession #: NP_005238.1
• NCBI GenBank Nucleotide #: NM_005247.2
• UniProt Accession #: P11487; Q0VG69
• Molecular Weight: 26,887 Da
• NCBI Official Full Name: fibroblast growth factor 3
• NCBI Official Synonym Full Names: fibroblast growth factor 3
• NCBI Official Symbol: FGF3
• NCBI Official Synonym Symbols: INT2; HBGF-3
• NCBI Protein Information: fibroblast growth factor 3; FGF-3; oncogene INT2; proto-oncogene Int-2; INT-2 proto-oncogene protein; heparin-binding growth factor 3; murine mammary tumor virus integration site 2, mouse; V-INT2 murine mammary tumor virus integration site oncogene homolo
• UniProt Protein Name: Fibroblast growth factor 3
• Protein Family: Fibroblast growth factor
• UniProt Gene Name: FGF3
• UniProt Synonym Gene Names: INT2; FGF-3; HBGF-3
• UniProt Entry Name: FGF3_HUMAN