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CXCL14 recombinant protein
CXCL14 Protein, Mouse, Recombinant
Gene Names
Cxcl14; KS1; Kec; BMAC; BRAK; NJAC; MIP-2g; Scyb14; AI414372; bolekine; MIP2gamma; 1110031L23Rik; 1200006I23Rik
Purity
>95% as determined by SDS-PAGE
Synonyms
CXCL14; CXCL14 Protein; Mouse; Recombinant; Mouse CXCL14/BRAK Protein; 1110031L23Rik Protein; 1200006I23Rik Protein; AI414372 Protein; BMAC Protein; bolekine Protein; BRAK Protein; Kec Protein; KS1 Protein; MIP-2g Protein; MIP2gamma Protein; NJAC Protein; Scyb14 Protein; chemokine (C-X-C motif) ligand 14; CXCL14 recombinant protein
Host
E Coli
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 100mM Na2HPO4, 1 M NaCl, pH6.5. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Ser23-Glu99
Species
Mouse
Predicted N Terminal
Ser 23
Tag
Native
Protein Construction
A DNA sequence encoding the mouse Cxcl14 (NP_062514.2)(Ser23-Glu99) was expressed.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
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SDS-Page
Related Product Information for CXCL14 recombinant protein
Background: CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,716 Da
NCBI Official Full Name
C-X-C motif chemokine 14
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 14
NCBI Official Symbol
Cxcl14
NCBI Official Synonym Symbols
KS1; Kec; BMAC; BRAK; NJAC; MIP-2g; Scyb14; AI414372; bolekine; MIP2gamma; 1110031L23Rik; 1200006I23Rik
NCBI Protein Information
C-X-C motif chemokine 14; B-cell and monocyte-activating chemokine; chemokine BRAK; kidney-expressed chemokine CXC; musculus CXC chemokine MIP-2gamma; small inducible cytokine subfamily B (Cys-X-Cys), member 14; small-inducible cytokine B14
UniProt Protein Name
C-X-C motif chemokine 14
Protein Family
UniProt Gene Name
Cxcl14
UniProt Synonym Gene Names
Bmac; Kec; Ks1; Mip2g; Scyb14
UniProt Entry Name
CXL14_MOUSE
Uniprot Description
CXCL14: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Chemokine
Cellular Component: Golgi apparatus; extracellular space; extracellular region
Molecular Function: chemokine activity; cytokine activity
Biological Process: immune response; negative regulation of myoblast differentiation; inner ear development
Research Articles on CXCL14
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Product Notes
The CXCL14 cxcl14 (Catalog #AAA8122554) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Ser23-Glu9 9. It is sometimes possible for the material contained within the vial of "CXCL14, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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