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LSM5 blocking peptide

LSM5 Immunizing Peptide

Gene Names
LSM5; YER146W
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Synonyms
LSM5; LSM5 Immunizing Peptide; LSM5 homolog; U6 small nuclear RNA associated (S. cerevisiae); FLJ12710; YER146W; OTTHUMP00000123495; OTTHUMP00000202663; OTTHUMP00000202664; OTTHUMP00000202665; OTTHUMP00000202666; OTTHUMP00000202667; U6 snRNA-associated Sm-like protein LSm5; LSM5 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Sequence
KCIGSRIHIVMKSDK
Sequence Length
91
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
6,850 Da
NCBI Official Full Name
U6 snRNA-associated Sm-like protein LSm5 isoform a
NCBI Official Synonym Full Names
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
NCBI Official Symbol
LSM5
NCBI Official Synonym Symbols
YER146W
NCBI Protein Information
U6 snRNA-associated Sm-like protein LSm5
UniProt Protein Name
U6 snRNA-associated Sm-like protein LSm5
Protein Family
UniProt Gene Name
LSM5
UniProt Entry Name
LSM5_HUMAN

NCBI Description

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]

Uniprot Description

LSM5: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. Belongs to the snRNP Sm proteins family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA processing

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: cytosol; nucleoplasm; nucleus; spliceosome; U4/U6 x U5 tri-snRNP complex

Molecular Function: protein binding; RNA binding

Biological Process: mRNA processing; nuclear mRNA splicing, via spliceosome

Research Articles on LSM5

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Product Notes

The LSM5 lsm5 (Catalog #AAA427822) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The LSM5 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Pig, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: KCIGSRIHIV MKSDK. It is sometimes possible for the material contained within the vial of "LSM5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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