Western Blot (WB)
(Western blotting analysis (reducing conditions) of whole cell lysate of HeLa human cervix carcinoma cell line.Lane 1: immunostaining with Isotype mouse IgG2b control (PLRV219)Lane 2: immunostaining with anti-SOCS3 (SO1))
Mouse anti-Human SOCS3 Antibody | anti-SOCS3 antibody
Anti-SOCS3 Purified
Gene Names
SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
SOCS3; Anti-SOCS3 Purified; suppressor of cytokine signaling 3; SOCS-3; CIS3; SSI3; anti-SOCS3 antibody
Host
Mouse
Reactivity
Human
Isotype
IgG2b
Clone Number
SO1
Specificity
The antibody SO1 reacts with SOCS3, an intracellular cytokine signaling inhibitor.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
225
Applicable Applications for anti-SOCS3 antibody
Western Blot (WB)
Immunogen
Full-length SOCS3 protein.
Preparation and Storage
Store at 2-8 degree C.
Western Blot (WB)
(Western blotting analysis (reducing conditions) of whole cell lysate of HeLa human cervix carcinoma cell line.Lane 1: immunostaining with Isotype mouse IgG2b control (PLRV219)Lane 2: immunostaining with anti-SOCS3 (SO1))
Western Blot (WB)
(Western blotting analysis (reducing conditions) of whole cell lysate of HeLa human cervix carcinoma cell line.Lane 1: immunostaining with Isotype mouse IgG2b control (PLRV219)Lane 2: immunostaining with anti-SOCS3 (SO1))
Related Product Information for anti-SOCS3 antibody
SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
SOCS3, partial
NCBI Official Synonym Full Names
suppressor of cytokine signaling 3
NCBI Official Symbol
SOCS3
NCBI Official Synonym Symbols
CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3
NCBI Protein Information
suppressor of cytokine signaling 3
UniProt Protein Name
SOCS3 protein
Protein Family
UniProt Gene Name
SOCS3
UniProt Entry Name
Q6FI39_HUMAN
NCBI Description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
Research Articles on SOCS3
Similar Products
Product Notes
The SOCS3 socs3 (Catalog #AAA1801550) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-SOCS3 Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SOCS3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the SOCS3 socs3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOCS3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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