CLEC3B / Tetranectin Recombinant Protein | CLEC3B recombinant protein
Recombinant Mouse CLEC3B / Tetranectin Protein (His tag)
Gene Names
Clec3b; Tna
Purity
> 95 % as determined by SDS-PAGE
Synonyms
CLEC3B / Tetranectin; Recombinant Mouse CLEC3B / Tetranectin Protein (His tag); Tna; CLEC3B recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
202
Application Notes
The recombinant mouse CLEC3B consists of 188 amino acids and predicts a molecular mass of 20.7 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCLEC3B is approximately 25 KDa.
Predicted N Terminal
Gln 22
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
Related Product Information for CLEC3B recombinant protein
Background: Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.
Description: A DNA sequence encoding the mouse CLEC3B (P43025) (Met 1-Val 202) was expressed, with a C-terminal polyhistidinetag.
Description: A DNA sequence encoding the mouse CLEC3B (P43025) (Met 1-Val 202) was expressed, with a C-terminal polyhistidinetag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,257 Da
NCBI Official Full Name
Tetranectin
NCBI Official Synonym Full Names
C-type lectin domain family 3, member b
NCBI Official Symbol
Clec3b
NCBI Official Synonym Symbols
Tna
NCBI Protein Information
tetranectin
UniProt Protein Name
Tetranectin
Protein Family
UniProt Gene Name
Clec3b
UniProt Synonym Gene Names
Tna; TN
Uniprot Description
CLEC3B: Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9 F4|9 73.91 cM
Cellular Component: cytoplasm; extracellular space; granular component; proteinaceous extracellular matrix
Molecular Function: calcium ion binding; carbohydrate binding; heparin binding; protein binding
Biological Process: bone mineralization; ossification; skeletal development
Research Articles on CLEC3B
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Product Notes
The CLEC3B clec3b (Catalog #AAA2546839) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse CLEC3B consists of 188 amino acids and predicts a molecular mass of 20.7 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCLEC3B is approximately 25 KDa. Researchers should empirically determine the suitability of the CLEC3B clec3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC3B / Tetranectin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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