Western Blot (WB)
(Western Blot analysis of Tetranectin on rat skin (1) and human skin (2) tissue lysates using anti-Tetranectin antibody at 1/1,000 dilution.)
Rabbit Tetranectin Polyclonal Antibody | anti-CLEC3B antibody
Tetranectin Polyclonal Antibody
Gene Names
CLEC3B; TN; TNA
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Purity
ProA affinity purified
Synonyms
Tetranectin; Polyclonal Antibody; Tetranectin Polyclonal Antibody; TN; CLEC3B; TNA; C type lectin domain family 3 member B; C-type lectin domain family 3 member B; Clec3b; Plasminogen kringle 4 binding protein; Plasminogen kringle 4-binding protein; TETN; Tetranectin (plasminogen binding protein); anti-CLEC3B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Tetranectin polyclonal antibody detects endogenous levels of Tetranectin protein.
Purity/Purification
ProA affinity purified
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
202
Applicable Applications for anti-CLEC3B antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes
WB: 1:1,000-1:5,000
ICC: 1:50-1:200
IHC: 1:50-1:200
IP: 1:10-1:50
ICC: 1:50-1:200
IHC: 1:50-1:200
IP: 1:10-1:50
Preparation and Storage
Store at 4 degree C after thawing.
Aliquot store at -20 degree C.
Avoid repeated freeze/thaw cycles.
Aliquot store at -20 degree C.
Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western Blot analysis of Tetranectin on rat skin (1) and human skin (2) tissue lysates using anti-Tetranectin antibody at 1/1,000 dilution.)
Western Blot (WB)
(Western Blot analysis of Tetranectin on rat skin (1) and human skin (2) tissue lysates using anti-Tetranectin antibody at 1/1,000 dilution.)
Immunocytochemistry (ICC)
(ICC staining Tetranectin in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Immunocytochemistry (ICC)
(ICC staining Tetranectin in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Related Product Information for anti-CLEC3B antibody
Tetranectin is a homotrimeric glycoprotein present in plasma and various tissue locations that binds to calcium, heparin, and plasminogen kringle 4. Tetranectin may play a prominent role in tissue remodeling as well as in the regulation of proteolytic processes via its binding and indirect activation of plasminogen. Tetranectin is found in the extracellular matrix (ECM) of certain carcinomas, but is not present in the ECM of normal tissues. Extracellular proteolysis is an important factor in the ability of malignant cells to penetrate normal tissues and metastasize. Decreased plasma tetranectin or increased tetranectin in stroma of cancers correlates with cancer progression and a grim prognosis. Tetranectin may also influence cancer growth by altering activities of plasminogen or the plasminogen fragment, angiostatin which inhibits tumor cell proliferation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22kDa
NCBI Official Full Name
Tetranectin
NCBI Official Synonym Full Names
C-type lectin domain family 3 member B
NCBI Official Symbol
CLEC3B
NCBI Official Synonym Symbols
TN; TNA
NCBI Protein Information
tetranectin
UniProt Protein Name
Tetranectin
Protein Family
UniProt Gene Name
CLEC3B
UniProt Synonym Gene Names
TNA; TN
UniProt Entry Name
TETN_HUMAN
Uniprot Description
CLEC3B: Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p22-p21.3
Cellular Component: extracellular matrix; extracellular space; granular component; cytoplasm; extracellular region
Molecular Function: heparin binding; calcium ion binding; carbohydrate binding
Biological Process: ossification; skeletal development; bone mineralization
Research Articles on CLEC3B
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Product Notes
The CLEC3B clec3b (Catalog #AAA3013551) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Tetranectin Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tetranectin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB: 1:1,000-1:5,000 ICC: 1:50-1:200 IHC: 1:50-1:200 IP: 1:10-1:50. Researchers should empirically determine the suitability of the CLEC3B clec3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tetranectin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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