CCL28 cdna clone
CCL28 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Uniprot Description
CCL28: Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Chemokine
Chromosomal Location of Human Ortholog: 5p12
Cellular Component: extracellular region
Molecular Function: chemokine activity; protein binding
Biological Process: chemotaxis; positive regulation of cell-matrix adhesion
Research Articles on CCL28
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Product Notes
The CCL28 ccl28 (Catalog #AAA1267573) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagcaga gaggactcgc catcgtggcc ttggctgtct gtgcggccct acatgcctca gaagccatac ttcccattgc ctccagctgt tgcacggagg tttcacatca tatttccaga aggctcctgg aaagagtgaa tatgtgtcgc atccagagag ctgatgggga ttgtgacttg gctgctgtca tccttcatgt caagcgcaga agaatctgtg tcagcccgca caaccatact gttaagcagt ggatgaaagt gcaagctgcc aagaaaaatg gtaaaggaaa tgtttgccac aggaagaaac accatggcaa gaggaacagt aacagggcac atcaggggaa acacgaaaca tacggccata aaactcctta ttag. It is sometimes possible for the material contained within the vial of "CCL28, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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