Rabbit anti-Human, Mouse CCL28 Polyclonal Antibody | anti-CCL28 antibody

CCL28 Rabbit Polyclonal

Cat. Num. AAA767615

• Gene Names: CCL28; MEC; CCK1; SCYA28
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: CCL28; Polyclonal Antibody; CCL28 Rabbit Polyclonal; anti-CCL28 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 80

• Applicable Applications for anti-CCL28 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Chemokine (C-C motif) ligand 28
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon using MBS767615 (CCL28 antibody) at dilution of 1:50)

Western Blot (WB)

(human spleen tissue were subjected to SDS PAGE followed by western blot with MBS767615 (CCL28 antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

• NCBI GI #: 687569497
• NCBI GeneID: 56477
• NCBI Accession #: NP_001288804.1
• NCBI GenBank Nucleotide #: NM_001301875.1
• Molecular Weight: 12,375 Da
• NCBI Official Full Name: C-C motif chemokine 28 isoform b
• NCBI Official Synonym Full Names: C-C motif chemokine ligand 28
• NCBI Official Symbol: CCL28
• NCBI Official Synonym Symbols: MEC; CCK1; SCYA28
• NCBI Protein Information: C-C motif chemokine 28
• UniProt Protein Name: C-C motif chemokine 28
• Protein Family: C-C motif chemokine
• UniProt Gene Name: CCL28
• UniProt Synonym Gene Names: SCYA28; MEC
• UniProt Entry Name: CCL28_HUMAN

NCBI Description

This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

Uniprot Description

CCL28: Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Chemokine; Secreted

Chromosomal Location of Human Ortholog: 5p12

Cellular Component: cytosol; extracellular region; extracellular space

Molecular Function: chemokine activity; protein binding

Biological Process: chemotaxis; elevation of cytosolic calcium ion concentration; immune response; positive regulation of cell-matrix adhesion