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HLADG/CD74 recombinant protein

Recombinant Mouse HLADG/CD74 Protein (C-mFc-6His)

Gene Names
Cd74; Ii; CLIP; DHLAG; HLADG; Ia-GAMMA
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
HLADG/CD74; Recombinant Mouse HLADG/CD74 Protein (C-mFc-6His); HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; CD74; Cluster of Differentiation 74; HLADG/CD74 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4.
Sequence Positions
Gln56-Leu215
Sequence Length
279
Species
Mouse
Endotoxin
<1.0 EU per mug as determined by LAL test.
Fusion Tag
C-mFc-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for HLADG/CD74 recombinant protein
Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 44.5 kDa
Actual Protein Molecular Mass: 45-55 kDa
NCBI Official Full Name
H-2 class II histocompatibility antigen gamma chain isoform 1
NCBI Official Synonym Full Names
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
NCBI Official Symbol
Cd74
NCBI Official Synonym Symbols
Ii; CLIP; DHLAG; HLADG; Ia-GAMMA
NCBI Protein Information
H-2 class II histocompatibility antigen gamma chain
UniProt Protein Name
H-2 class II histocompatibility antigen gamma chain
UniProt Gene Name
Cd74
UniProt Synonym Gene Names
Ii; Ii

Uniprot Description

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.

Research Articles on HLADG/CD74

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Product Notes

The HLADG/CD74 cd74 (Catalog #AAA2553514) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Gln56-Leu215. It is sometimes possible for the material contained within the vial of "HLADG/CD74, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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