CD5L / API6 recombinant protein
Recombinant Human CD5L / API6 Protein (His tag)
Gene Names
CD5L; AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA
Purity
> 97 % as determined by SDS-PAGE
Synonyms
CD5L / API6; Recombinant Human CD5L / API6 Protein (His tag); UNQ203/PRO229; AIM; API6; PRO229; SP-ALPHA; Spalpha; CD5L; CD5L / API6 recombinant protein
Host
Human Cells
Purity/Purification
> 97 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
347
Application Notes
The secreted recombinant human CD5L comprises 339 amino acids and has a predicted molecular mass of 37.5 kDa. As a result of glycosylation, rhCD5L migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Ser 20
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
Related Product Information for CD5L / API6 recombinant protein
Background: CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.
Description: A DNA sequence encoding the human CD5L (NP_005885.1) (Met 1-Gly 347) with a C-terminal polyhistidine tag was expressed.
Description: A DNA sequence encoding the human CD5L (NP_005885.1) (Met 1-Gly 347) with a C-terminal polyhistidine tag was expressed.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,088 Da
NCBI Official Full Name
CD5 antigen-like isoform 1
NCBI Official Synonym Full Names
CD5 molecule like
NCBI Official Symbol
CD5L
NCBI Official Synonym Symbols
AIM; API6; CT-2; hAIM; PRO229; Spalpha; SP-ALPHA
NCBI Protein Information
CD5 antigen-like
UniProt Protein Name
CD5 antigen-like
UniProt Gene Name
CD5L
UniProt Synonym Gene Names
API6; hAIM
Uniprot Description
CD5L: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.
Protein type: Receptor, misc.; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: extracellular space
Biological Process: cellular defense response
Research Articles on CD5L / API6
Similar Products
Product Notes
The CD5L / API6 cd5l (Catalog #AAA2546084) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant human CD5L comprises 339 amino acids and has a predicted molecular mass of 37.5 kDa. As a result of glycosylation, rhCD5L migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CD5L / API6 cd5l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD5L / API6, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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