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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland using MBS1498142 at dilution 1:100)

Rabbit anti-Human HYLS1 Polyclonal Antibody | anti-HYLS1 antibody

HYLS1 Antibody

Gene Names
HYLS1; HLS
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
HYLS1; Polyclonal Antibody; HYLS1 Antibody; HLS; anti-HYLS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
299
Applicable Applications for anti-HYLS1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Hydrolethalus syndrome protein 1 protein (70-299aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161720 / sc-161721
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human adrenal gland using MBS1498142 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland using MBS1498142 at dilution 1:100)
Related Product Information for anti-HYLS1 antibody
HYLS1, also named as HLS, is widely expressed in fetal tissue. Mutation of HYLS1 will cause the hydrolethalus syndrome (HLS) which is an autosomal recessive lethal malformation syndrome characterized by multiple developmental defects of fetus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,359 Da
NCBI Official Full Name
hydrolethalus syndrome protein 1
NCBI Official Synonym Full Names
hydrolethalus syndrome 1
NCBI Official Symbol
HYLS1
NCBI Official Synonym Symbols
HLS
NCBI Protein Information
hydrolethalus syndrome protein 1
UniProt Protein Name
Hydrolethalus syndrome protein 1
UniProt Gene Name
HYLS1
UniProt Synonym Gene Names
HLS
UniProt Entry Name
HYLS1_HUMAN

NCBI Description

This gene encodes a protein localized to the cytoplasm. Mutations in this gene are associated with hydrolethalus syndrome. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]

Uniprot Description

HYLS1: Defects in HYLS1 are the cause of hydrolethalus syndrome type 1 (HLS1). HLS1 is a lethal malformation syndrome leading to stillbirth or death shortly after birth. It is characterized by hydrocephaly with absent upper midline structures of the brain, micrognathia and polydactyly. Belongs to the HYLS1 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: centrosome; cytoplasm; nucleus; plasma membrane

Molecular Function: protein binding

Disease: Hydrolethalus Syndrome 1

Research Articles on HYLS1

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Product Notes

The HYLS1 hyls1 (Catalog #AAA1498142) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HYLS1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HYLS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the HYLS1 hyls1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HYLS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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