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NEUCRIN Blocking Peptide | C1orf187 blocking peptide

NEUCRIN Peptide

Gene Names
DRAXIN; UNQ3119; neucrin; AGPA3119; C1orf187
Applications
Blocking (BL)
Synonyms
NEUCRIN; NEUCRIN Peptide; UNQ3119; neucrin; AGPA3119; C1orf187; PSEC0258; UNQ3119/PRO10268; Draxin; Dorsal inhibitory axon guidance protein; chromosome 1 open reading frame 187; C1orf187 blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
349
Applicable Applications for C1orf187 blocking peptide
Blocking (BL)
Application Notes
NEUCRIN peptide is used for blocking the activity of NEUCRIN antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
20 amino acids near the carboxy terminus of human ECRG4.
Preparation and Storage
Store NEUCRIN peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,650 Da
NCBI Official Full Name
draxin
NCBI Official Synonym Full Names
dorsal inhibitory axon guidance protein
NCBI Official Symbol
DRAXIN
NCBI Official Synonym Symbols
UNQ3119; neucrin; AGPA3119; C1orf187
NCBI Protein Information
draxin; dorsal repulsive axon guidance protein; dorsal inhibitory axon guidance protein; neural tissue-specific cysteine-rich protein
UniProt Protein Name
Draxin
UniProt Gene Name
DRAXIN
UniProt Entry Name
DRAXI_HUMAN

Uniprot Description

DRAXIN: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta- catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. Belongs to the draxin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: extracellular region

Biological Process: dorsal spinal cord development; axon guidance; Wnt receptor signaling pathway; forebrain development; commissural neuron differentiation in the spinal cord; negative regulation of axon extension; negative regulation of neuron apoptosis

Research Articles on C1orf187

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Product Notes

The C1orf187 draxin (Catalog #AAA153280) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NEUCRIN can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). NEUCRIN peptide is used for blocking the activity of NEUCRIN antibody. Researchers should empirically determine the suitability of the C1orf187 draxin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEUCRIN, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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