ZBTB42 blocking peptide
ZBTB42 Antibody (N-term) Blocking peptide
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the C2H2 zinc finger protein family. This protein is predicted to have a pox virus and zinc finger (POZ) domain at the N-terminus and four zinc finger domains at the C-terminus. In human and mouse, the protein localizes to the nuclei of skeletal muscle cells. Knockdown of this gene in zebrafish results in abnormal skeletal muscle development and myofibrillar disorganization. A novel homozygous variant of the human gene has been associated with lethal congenital contracture syndrome, an autosomal recessive disorder that results in muscle wasting. [provided by RefSeq, Mar 2015]
Uniprot Description
ZBTB42: Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes. Belongs to the krueppel C2H2-type zinc-finger protein family. ZNF238 subfamily.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleoplasm; nucleus; plasma membrane
Biological Process: muscle development
Disease: Lethal Congenital Contracture Syndrome 6
Research Articles on ZBTB42
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Product Notes
The ZBTB42 zbtb42 (Catalog #AAA9218502) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZBTB42, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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