Rabbit anti-Mouse ZBTB42 Polyclonal Antibody | anti-ZBTB42 antibody

ZBTB42, NT (ZBTB42, Zinc finger and BTB domain-containing protein 42) (AP)

Cat. Num. AAA6364655

• Gene Names: ZBTB42; LCCS6; ZNF925
• Reactivity: Mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ZBTB42; Polyclonal Antibody; NT (ZBTB42; Zinc finger and BTB domain-containing protein 42) (AP); Zinc finger and BTB domain-containing protein 42; anti-ZBTB42 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-ZBTB42 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:50-100; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: ZBTB42 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human ZBTB42.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ZBTB42 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ZBTB42 antibody detected the ZBTB42 protein (arrow).)

Immunohistochemistry (IHC)

(ZBTB42 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZBTB42 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-ZBTB42 antibody

Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes (By similarity).

Product Categories/Family for anti-ZBTB42 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

References

Bailey, S.D., et al. Diabetes Care (2010). In press: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 212286156
• NCBI GeneID: 100128927
• NCBI Accession #: NP_001131073.1
• NCBI GenBank Nucleotide #: NM_001137601.1
• UniProt Accession #: B2RXF5; B7ZW21
• Molecular Weight: 46,491 Da
• NCBI Official Full Name: zinc finger and BTB domain-containing protein 42
• NCBI Official Synonym Full Names: zinc finger and BTB domain containing 42
• NCBI Official Symbol: ZBTB42
• NCBI Official Synonym Symbols: LCCS6; ZNF925
• NCBI Protein Information: zinc finger and BTB domain-containing protein 42
• UniProt Protein Name: Zinc finger and BTB domain-containing protein 42
• Protein Family: Zinc finger and BTB domain-containing protein
• UniProt Gene Name: ZBTB42
• UniProt Entry Name: ZBT42_HUMAN

NCBI Description

The protein encoded by this gene is a member of the C2H2 zinc finger protein family. This protein is predicted to have a pox virus and zinc finger (POZ) domain at the N-terminus and four zinc finger domains at the C-terminus. In human and mouse, the protein localizes to the nuclei of skeletal muscle cells. Knockdown of this gene in zebrafish results in abnormal skeletal muscle development and myofibrillar disorganization. A novel homozygous variant of the human gene has been associated with lethal congenital contracture syndrome, an autosomal recessive disorder that results in muscle wasting. [provided by RefSeq, Mar 2015]