Western Blot (WB)
(ZBTB42 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ZBTB42 antibody detected the ZBTB42 protein (arrow).)
Rabbit anti-Mouse ZBTB42 Polyclonal Antibody | anti-ZBTB42 antibody
ZBTB42 Antibody (N-term)
Western Blot (WB)
(ZBTB42 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ZBTB42 antibody detected the ZBTB42 protein (arrow).)
Western Blot (WB)
(ZBTB42 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the ZBTB42 antibody detected the ZBTB42 protein (arrow).)
Immunohistochemistry (IHC)
(ZBTB42 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZBTB42 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ZBTB42 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZBTB42 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the C2H2 zinc finger protein family. This protein is predicted to have a pox virus and zinc finger (POZ) domain at the N-terminus and four zinc finger domains at the C-terminus. In human and mouse, the protein localizes to the nuclei of skeletal muscle cells. Knockdown of this gene in zebrafish results in abnormal skeletal muscle development and myofibrillar disorganization. A novel homozygous variant of the human gene has been associated with lethal congenital contracture syndrome, an autosomal recessive disorder that results in muscle wasting. [provided by RefSeq, Mar 2015]
Uniprot Description
ZBTB42: Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes. Belongs to the krueppel C2H2-type zinc-finger protein family. ZNF238 subfamily.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
Disease: Lethal Congenital Contracture Syndrome 6
Research Articles on ZBTB42
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Product Notes
The ZBTB42 zbtb42 (Catalog #AAA9201909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 37-65. The ZBTB42 Antibody (N-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZBTB42 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the ZBTB42 zbtb42 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZBTB42, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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