PEX11A recombinant protein

PEX11A Protein, Human, Recombinant (mFc Tag)

Cat. Num. AAA8121615

• Gene Names: PEX11A; PMP28; hsPEX11p; PEX11-ALPHA
• Purity: >90% as determined by SDS-PAGE
• Synonyms: PEX11A; PEX11A Protein; Human; Recombinant (mFc Tag); Human PEX11A/Peroxin-11A Protein (Fc Tag); hsPEX11p Protein; PEX11-ALPHA Protein; PMP28 Protein; peroxisomal biogenesis factor 11 alpha; PEX11A recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Arg106-Pro219

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Asp
• Tag: N-mouse IgG1-Fc
• Protein Construction: A DNA sequence encoding the human PEX11A (NP_003838.1)(Arg106-Pro219) was expressed with the Fc region of mouse IgG1 at the N-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 4505717
• NCBI GeneID: 8800
• NCBI Accession #: NP_003838.1
• NCBI GenBank Nucleotide #: NM_003847.2
• UniProt Accession #: O75192
• Molecular Weight: 28,353 Da
• NCBI Official Full Name: peroxisomal membrane protein 11A isoform 1
• NCBI Official Synonym Full Names: peroxisomal biogenesis factor 11 alpha
• NCBI Official Symbol: PEX11A
• NCBI Official Synonym Symbols: PMP28; hsPEX11p; PEX11-ALPHA
• NCBI Protein Information: peroxisomal membrane protein 11A; peroxin-11A; protein PEX11 homolog alpha; peroxisomal biogenesis factor 11A; 28 kDa peroxisomal integral membrane protein
• UniProt Protein Name: Peroxisomal membrane protein 11A
• Protein Family: Peroxisomal membrane protein
• UniProt Gene Name: PEX11A
• UniProt Synonym Gene Names: PEX11; HsPEX11p; PMP28; PEX11-alpha
• UniProt Entry Name: PX11A_HUMAN

NCBI Description

This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside stimuli to increase peroxisome abundance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]

Uniprot Description

PEX11A: May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane. Belongs to the peroxin-11 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q26.1

Cellular Component: peroxisomal membrane; integral to peroxisomal membrane; protein complex; peroxisome

Molecular Function: protein binding; protein homodimerization activity

Biological Process: peroxisome fission; peroxisome organization and biogenesis; brown fat cell differentiation; cellular lipid metabolic process; signal transduction; peroxisome membrane biogenesis