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OSBPL1A blocking peptide

OSBPL1A Antibody (C-term) Blocking Peptide

Gene Names
OSBPL1A; ORP1; ORP-1; OSBPL1B
Synonyms
OSBPL1A; OSBPL1A Antibody (C-term) Blocking Peptide; Oxysterol-binding protein-related protein 1; ORP-1; OSBP-related protein 1; ORP1; OSBP8; OSBPL1; OSBPL1B; OSBPL1A blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
950
Cellular Location
Late endosome. Note: Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for OSBPL1A blocking peptide
Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
65,095 Da
NCBI Official Full Name
Oxysterol-binding protein-related protein 1
NCBI Official Synonym Full Names
oxysterol binding protein like 1A
NCBI Official Symbol
OSBPL1A
NCBI Official Synonym Symbols
ORP1; ORP-1; OSBPL1B
NCBI Protein Information
oxysterol-binding protein-related protein 1
UniProt Protein Name
Oxysterol-binding protein-related protein 1
UniProt Gene Name
OSBPL1A
UniProt Synonym Gene Names
ORP1; OSBP8; OSBPL1; OSBPL1B; ORP-1; OSBP-related protein 1
UniProt Entry Name
OSBL1_HUMAN

NCBI Description

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

OSBPL1A: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Belongs to the OSBP family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q11.1

Cellular Component: cytoplasm; intracellular; late endosome; lysosomal membrane; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II

Research Articles on OSBPL1A

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Product Notes

The OSBPL1A osbpl1a (Catalog #AAA9222032) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "OSBPL1A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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