Structure
Probucol Biochemical
Probucol
Purity
>98%
Synonyms
Probucol; 2; 6-ditert-butyl-4-[2- (3; 5-ditert-butyl-4-hydroxyphenyl) sulfanylpropan-2-ylsulfanyl]phenol; Lorelco; Biphenabid; Bisphenabid; NSC 86225; NSC 652160; DH 581; 4; 4'-[ (1-Methylethylidene) bis (thio) ]bis[2; 6-bis (1; 1-dimethylethyl) phenol]; Acetone bis (3; 5-di-tert-butyl-4-hydroxyphenyl) mercaptole; 4'- (Isopropylidenedithio) bis (2; 6-di-tert-butylphenol); Probucol biochemical
Purity/Purification
>98%
Form/Format
Solid
Solubility
~25 mg/ml in Ethanol
~30 mg/ml in DMF
~20 mg/ml in DMSO
~30 mg/ml in DMF
~20 mg/ml in DMSO
Molecular Formula
C??H??O?S?
CAS Number
23288-49-5
MDL Number
MFCD00079281
PubChem CID
4912
SMILES
CC (C)(C)C1=CC (=CC (=C1O)C (C)(C)C)SC (C)(C)SC2=CC (=C (C (=C2)C (C)(C)C)O)C (C)(C)C
InChi
InChI=1S/C31H48O2S2/c1-27 (2,3)21-15-19 (16-22 (25 (21)32)28 (4,5)6)34-31 (13,14)35-20-17-23 (29 (7,8)9)26 (33)24 (18-20)30 (10,11)12/h15-18,32-33H,1-14H3
InChi Key
FYPMFJGVHOHGLL-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for Probucol biochemical
Probucol is a potent antioxidant that inhibits the oxidation of cholesterol in LDL which prevents the formation of macrophage-derived foam cells that lead to atherosclerotic vascular lesions. The use of probucol is limited, because it leads to the reduction of HDL cholesterol. Probucol inhibits cholesterol efflux up to 80% in J774 macrophages expressing ATP-binding cassette transporter A1 (ABCA1) by inhibiting ABCA1 translocation to the plasma membrane. Administration of probucol at 3.5 mg/kg/day for 2 months increases the activity of glutathione peroxidase in an in vivo mouse model of Huntington's disease and is protective against behavioral and striatal oxidative damage.
Product Categories/Family for Probucol biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/4912
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Product Notes
The Probucol (Catalog #AAA849063) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Probucol, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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