Structure
Licogliflozin Biochemical
Licogliflozin
Purity
>=98%
Synonyms
Licogliflozin; LIK066; (2S; 3R; 4R; 5S; 6R)-2-[3-(2; 3-dihydro-1; 4-benzodioxin-6-ylmethyl)-4-ethylphenyl]-6-(hydroxymethyl)oxane-3; 4; 5-triol; 3-dihydro-benzo[1; 4]dioxin-6-ylmethyl)-4-ethyl-phenyl]-6-hydroxymethyl-tetrahydro-pyran-3; Licogliflozin biochemical
Specificity
A dual inhibitor of Sodium/glucose cotransporters SGLT1 and SGLT2
Purity/Purification
>=98%
Form/Format
Solid
Solubilities
Soluble in DMSO
Molecular Formula
C??H??O?
InChi
InChI=1S/C23H28O7/c1-2-14-4-5-15(23-22(27)21(26)20(25)19(12-24)30-23)11-16(14)9-13-3-6-17-18(10-13)29-8-7-28-17/h3-6; 10-11; 19-27H; 2; 7-9; 12H2; 1H3/t19-; 20-; 21+; 22-; 23+/m1/s1
InChi Key
XFJAMQQAAMJFGB-ZQGJOIPISA-N
SMILES
CCC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC4=C(C=C3)OCCO4
CAS Number
1291094-73-9
MDL Number
MFCD31630771
PubChem CID
52913524
Preparation and Storage
Store at -20 degree C
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Shelf Life: Est.~36 months
Country of Origin: USA
Structure
Structure
Related Product Information for Licogliflozin biochemical
Licogliflozin is a dual inhibitor of Sodium/glucose cotransporters SGLT1 and SGLT2 with a higher selectivity for SGLT2 (in vitro IC50 values of 20.6 and 0.58nM, respectively). It causes a reduction in body weight from baseline versus placebo after 24 weeks (50mg twice daily). However, the percent decreases were numerically small (<5%). Higher doses of licogliflozin also reduce waist circumference, fasting plasma glucose, hemoglobin A1c (HbA1c), systolic blood pressure and triglycerides. It increases HDL cholesterol and 24?hour urinary glucose excretion.
Product Categories/Family for Licogliflozin biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/52913524
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Product Notes
The Licogliflozin (Catalog #AAA8400469) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Licogliflozin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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