Structure
RTA 408 Biochemical
RTA 408
Purity
>=98%
Synonyms
RTA 408; N-[ (4aS; 6aR; 6bS; 8aR; 12aS; 14aR; 14bS)-11-cyano-2; 2; 6a; 6b; 9; 12a-heptamethyl-10; 14-dioxo-1; 3; 4; 5; 6; 7; 8; 8a; 14a; 14b-decahydropicen-4a-yl]-2; 2-difluoropropanamide; Omaveloxolone; N- (2-cyano-3; 12-dioxo-28-noroleana-1; 9 (11)-dien-17-yl)-2; N- ( (4aS; 4a; 10; 12a; 14; 14b-octadecahydropicen-4a-yl)-2; RTA 408 biochemical
Purity/Purification
>=98%
Form/Format
A crystalline solid
Solubility
~2 mg/ml in ethanol
DMSO and DMF
DMSO and DMF
Molecular Formula
C??H??F?N?O?
CAS Number
1474034-05-3
PubChem CID
71811910
SMILES
CC1 (CCC2 (CCC3 (C (C2C1)C (=O)C=C4C3 (CCC5C4 (C=C (C (=O)C5 (C)C)C#N)C)C)C)NC (=O)C (C)(F)F)C
InChi
InChI=1S/C33H44F2N2O3/c1-27 (2)11-13-33 (37-26 (40)32 (8,34)35)14-12-31 (7)24 (20 (33)17-27)21 (38)15-23-29 (5)16-19 (18-36)25 (39)28 (3,4)22 (29)9-10-30 (23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3, (H,37,40)/t20-,22-,24-,29-,30+,31+,33-/m0/s1
InChi Key
RJCWBNBKOKFWNY-IDPLTSGASA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for RTA 408 biochemical
RTA 408 is a synthetic oleanane triterpenoid that activates Nrf2. RTA 408 activates Nrf2 and suppresses nitric oxide and pro-inflammatory cytokine levels in interferon-gamma-stimulated RAW 264.7 macrophage cells at low concentrations (<= 25 nM). It inhibits growth of tumor cells with a GI50 value of 260 +/- 74 nM. Topical application of RTA 408 induces cytoprotective genes and protects mice from radiation-induced dermatitis.
Product Categories/Family for RTA 408 biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/71811910
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Product Notes
The RTA 408 (Catalog #AAA848995) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RTA 408, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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