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Structure

Bisdemethoxycurcumin Biochemical

Bisdemethoxycurcumin

Purity
>98%
Synonyms
Bisdemethoxycurcumin; (1E; 6E)-1; 7-bis (4-hydroxyphenyl) hepta-1; 6-diene-3; 5-dione; Didemethoxycurcumin; Curcumin III; Bis (4-hydroxycinnamoyl) methane; Bis (p-hydroxycinnamoyl) methane; Curcuminoid A; Curcumin Lll; DidemethoxycurcumiI; di-p-coumaroylmethane; 1; 3-Di (4-hydroxystyryl) propanedial; 7-bis (4-hydroxyphenyl)-3-hydroxy-1; 3; 6-heptatrien-5-one; BDMC; Bisdemethoxycurcumin biochemical
Ordering
For Research Use Only!
Purity/Purification
>98%
Form/Format
A crystalline solid
Solubility
~5 mg/ml in Ethanol
~14 mg/ml in DMF
~10 mg/ml in DMSO
Molecular Formula
C??H??O?
CAS Number
24939-16-0, 33171-05-0
PubChem CID
5315472
SMILES
C1=CC (=CC=C1C=CC (=O)CC (=O)C=CC2=CC=C (C=C2)O)O
InChi
InChI=1S/C19H16O4/c20-16-7-1-14 (2-8-16)5-11-18 (22)13-19 (23)12-6-15-3-9-17 (21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+
InChi Key
PREBVFJICNPEKM-YDWXAUTNSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36months

Structure

Structure
Related Product Information for Bisdemethoxycurcumin biochemical
Bisdemethoxycurcumin is a curcumin analogue with anti-inflammatory and anti-proliferative properties. It suppresses tumor necrosis factor (TNF) -induced nuclear factor-kappaB (NF-kappaB) activation in KBM-5 cells and inhibits proliferation of different cell lines at 25 uM. Bisdemethoxycurcumin enhances phagocytosis of amyloid-beta and transcription of MGAT3 and TLR. It down-regulates the transcriptional coactivator p300 and thereby inhibits the Wnt/beta-catenin pathway. It inhibits inducible nitric oxide synthase protein expression and accelerates healing of gastric ulcer in a rat model.
References
https://pubchem.ncbi.nlm.nih.gov/compound/5315472

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Product Notes

The Bisdemethoxycurcumin (Catalog #AAA849039) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bisdemethoxycurcumin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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