Structure
BRD9539 Biochemical
BRD9539
Purity
>=98%
Synonyms
BRD9539; 2-benzamido-1- (3-phenylpropyl) benzimidazole-5-carboxylic acid; BRD9539 biochemical
Purity/Purification
>=98%
Form/Format
Crystalline solid
Solubility
0.5 mg/ml in Ethanol
10 mg/ml in DMSO and DMF
10 mg/ml in DMSO and DMF
Molecular Formula
C??H??N?O?
CAS Number
1374601-41-8
PubChem CID
73755260
SMILES
C1=CC=C (C=C1)CCCN2C3=C (C=C (C=C3)C (=O)O)N=C2NC (=O)C4=CC=CC=C4
InChi
InChI=1S/C24H21N3O3/c28-22 (18-11-5-2-6-12-18)26-24-25-20-16-19 (23 (29)30)13-14-21 (20)27 (24)15-7-10-17-8-3-1-4-9-17/h1-6,8-9,11-14,16H,7,10,15H2, (H,29,30)(H,25,26,28)
InChi Key
WPXMEOBILYVKBC-UHFFFAOYSA-N
Preparation and Storage
Store at -20 degree C
Shelf life: ~36 months
Shelf life: ~36 months
Structure
Structure
Related Product Information for BRD9539 biochemical
BRD9539 is a specific inhibitor of euchromatin histone methyltransferase G9a (EHMT2). EHMT2 catalyzes the methylation of lysine 9 on histone H3. BRD9539 inhibits EHMT2 with an IC50 of 6.3 uM. It also inhibits methyl transferase PRC2 with a similar IC50. It is the methyl-ester analogue of BRD4770. It is more potent than BRD4770 in enzyme assays but does not show activity in cell-based assays, probably due to impaired cell permeability compared to that of BRD4770.
Product Categories/Family for BRD9539 biochemical
References
https://pubchem.ncbi.nlm.nih.gov/compound/73755260
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Product Notes
The BRD9539 (Catalog #AAA848945) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BRD9539, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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