Principle of the Assay: Hypoxanthine are oxidized by xanthine oxidase (XOD) to produce xanthine and super oxygen anion, which will quickly converte to hydrogen peroxide in the system, and then, in the role of peroxidase, hydrogen peroxide can oxidize the non-fluorescent probe to fluorescent substance. By measuring the fluorescence value, the corresponding the activity of xanthine oxidase can be calculated.
Background/Introduction: Xanthine oxidase (XOD) is widely distributed in the tissue and cell cytoplasm of human heart, lung, liver and so on, and the mucosa of small intestine is the most abundant. XOD in serum mainly comes from liver cells. When liver cells are damaged, the content of XOD in serum will increase sharply, which is of great significance for the identification of hepatocellular jaundice and obstructive jaundice. In addition, when XOD is abnormally active in the body, it will lead to the generation and excessive accumulation of a large amount of uric acid, leading to hyperuricemia and gout.
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Product Notes
The XOD (Catalog #AAA2567665) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Xanthine Oxidase (XOD), Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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