Western Blot (WB)
(Western Blot analysis of 3T3 cells with Phospho-Syk (Tyr348) Polyclonal Antibody)
Syk antibody kit
Phospho-Syk Antibody Sampler Kit
Applications
Western Blot
Synonyms
Syk; Phospho-Syk Antibody Sampler Kit; Syk antibody kit
Applicable Applications for Syk antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of 3T3 cells with Phospho-Syk (Tyr348) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of 3T3 cells with Phospho-Syk (Tyr348) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of COS7 cells with Phospho-Syk (Tyr525) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of COS7 cells with Phospho-Syk (Tyr525) Polyclonal Antibody)
Related Product Information for Syk antibody kit
Background: Syk is a protein tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cells. Syk interacts with immunoreceptor tyrosine-based activation motifs (ITAMs) located in the cytoplasmic domains of immune receptors. It couples the activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. There is also evidence of a role for Syk in nonimmune cells and investigators have indicated that Syk is a potential tumor suppressor in human breast carcinomas. Tyr323 is a negative regulatory phosphorylation site within the SH2-kinase linker region in Syk. Phosphorylation at Tyr323 provides a direct binding site for the TKB domain of Cbl. Tyr352 of Syk is involved in the association of PLCgamma1. Tyr525 and Tyr526 are located in the activation loop of the Syk kinase domain; phosphorylation at Tyr525/526 of human Syk (equivalent to Tyr519/520 of mouse Syk) is essential for Syk function.
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Product Notes
The Syk (Catalog #AAA2550080) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Syk can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Syk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syk, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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