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Western Blot (WB)
(Western Blot analysis of 293 cells using PLC gamma1 Polyclonal Antibody at dilution of 1:2000.)
PLCgamma antibody kit
PLCgamma Antibody Sampler Kit
Applications
Western Blot
Synonyms
PLCgamma; PLCgamma Antibody Sampler Kit; PLCgamma antibody kit
Applicable Applications for PLCgamma antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of 293 cells using PLC gamma1 Polyclonal Antibody at dilution of 1:2000.)
Western Blot (WB)
(Western Blot analysis of 293 cells using PLC gamma1 Polyclonal Antibody at dilution of 1:2000.)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-PLC gamma1 (Tyr783) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-PLC gamma1 (Tyr783) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of COS7 cells with Phospho-PLC gamma1 (Tyr771) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of COS7 cells with Phospho-PLC gamma1 (Tyr771) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of 1) KB, 2) 3T3 cells using PLC gamma2 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of 1) KB, 2) 3T3 cells using PLC gamma2 Polyclonal Antibody at dilution of 1:1000.)
Western Blot (WB)
(Western Blot analysis of HepG2 cells with Phospho-PLC gamma2 (Tyr753) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of HepG2 cells with Phospho-PLC gamma2 (Tyr753) Polyclonal Antibody)
Related Product Information for PLCgamma antibody kit
Background: Phosphoinositide-specific phospholipase C (PLC) plays a significant role in transmembrane signaling. In response to extracellular stimuli such as hormones, growth factors, and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). At least four families of PLCs have been identified: PLCbeta, PLCgamma, PLCdelta, and PLCepsilon. Phosphorylation is one of the key mechanisms that regulate the activity of PLC. PLCgamma is activated by both receptor and non-receptor tyrosine kinases. PLCgamma forms a complex with EGF and PDGF receptors, which leads to the phosphorylation of PLCgamma at Tyr771, 783, and 1248. Phosphorylation by Syk at Tyr783 activates the enzymatic activity of PLCgamma1. PLCgamma2 is engaged in antigen-dependent signaling in B cells and collagen-dependent signaling in platelets. Phosphorylation by Btk or Lck at Tyr753, 759, 1197, and 1217 is correlated with PLCgamma2 activity.
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Product Notes
The PLCgamma (Catalog #AAA2550072) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PLCgamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PLCgamma for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCgamma, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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