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Western Blot (WB)
(Western Blot analysis of 453 cells with Phospho-JAK3 (Tyr785) Polyclonal Antibody at dilution of 1:1000)
ALK Activation Antibody Kit | ALK antibody kit
ALK Activation Antibody Sampler Kit
Applications
Western Blot
Synonyms
ALK Activation; ALK Activation Antibody Sampler Kit; ALK antibody kit
Applicable Applications for ALK antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of 453 cells with Phospho-JAK3 (Tyr785) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of 453 cells with Phospho-JAK3 (Tyr785) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of 3T3 cells with Phospho-JAK2 (Tyr1007) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of 3T3 cells with Phospho-JAK2 (Tyr1007) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of KB, MCF7 cells with Phospho-Stat3 (Tyr705) Polyclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of KB, MCF7 cells with Phospho-Stat3 (Tyr705) Polyclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of Hela cells using Phospho-Stat5 (Ser726/731) Polyclonal Antibody at dilution of 1:500.)
Western Blot (WB)
(Western Blot analysis of Hela cells using Phospho-Stat5 (Ser726/731) Polyclonal Antibody at dilution of 1:500.)
Western Blot (WB)
(Western Blot analysis of Hela, 293 cells with Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Hela, 293 cells with Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of MCF7 cells with Phospho-Akt (Ser473) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of MCF7 cells with Phospho-Akt (Ser473) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-c-Src (Tyr419) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-c-Src (Tyr419) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-PLC gamma1 (Tyr783) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of 293 cells with Phospho-PLC gamma1 (Tyr783) Polyclonal Antibody)
Related Product Information for ALK antibody kit
Background: Anaplastic lymphoma kinase (ALK) is a tyrosine kinase receptor for pleiotrophin (PTN), a growth factor involved in embryonic brain development. In ALK-expressing cells, PTN induces phosphorylation of both ALK and the downstream effectors IRS-1, Shc, PLCgamma, and PI3 kinase. ALK was originally discovered as a nucleophosmin (NPM)-ALK fusion protein produced by a translocation. Investigators have found that the NPM-ALK fusion protein is a constitutively active, oncogenic tyrosine kinase associated with anaplastic lymphoma. Research literature suggests that activation of PLCgamma by NPM-ALK may be a crucial step for its mitogenic activity and involved in the pathogenesis of anaplastic lymphomas. A distinct ALK oncogenic fusion protein involving ALK and echinoderm microtubule-associated protein like 4 (EML4) has been described in the research literature from a non-small cell lung cancer (NSCLC) cell line, with corresponding fusion transcripts present in some cases of lung adenocarcinoma. The short, amino-terminal region of the microtubule-associated protein EML4 is fused to the kinase domain of ALK.
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Product Notes
The ALK (Catalog #AAA2549978) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ALK Activation can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ALK for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALK Activation, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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