Complement C2 (C2) Recombinant Protein | C2 recombinant protein
Recombinant Mouse Complement C2 (C2)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Complement C2 (C2); Recombinant Mouse Complement C2 (C2); C2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
19-760, Full length protein
Sequence
ALFCNQNVNITGGNFTLSHGWAPGSLLIYSCPLGRYPSPAWRKCQSNGQWLTPRSSSHHTLRSSRMVKAVCKPVRCLAPSSFENGIYFPRLVSYPVGSNVSFECEQDFTLRGSPVRYCRPNGLWDGETAVCDNGASHCPNPGISVGTARTGLNFDLGDKVRYRCSSSNMVLTGSAERECQSNGVWSGSEPICRQPYSYDFPEDVASALDTSLTNLLGATNPTQNLLTKSLGRKIIIQRSGHLNLYLLLDASQSVTEKDFDIFKKSAELMVERIFSFEVNVSVAIITFASQPKTIMSILSERSQDVTEVITSLDSASYKDHENATGTNTYEVLIRVYSMMQSQMDRLGMETSAWKEIRHTIILLTDGKSNMGDSPKKAVTRIRELLSIEQNRDDYLDIYAIGVGKLDVDWKELNELGSKKDGERHAFILQDAKALQQIFEHMLDVSKLTDTICGVGNMSANASDQERTPWQVTFKPKSKETCQGSLISDQWVLTAAHCFHDIQMEDHHLWRVNVGDPTSQHGKEFLVEDVIIAPGFNVHAKRKQGISEFYADDIALLKLSRKVKMSTHARPICLPCTVGANMALRRSPGSTCKDHETELLSQQKVPAHFVALNGNRLNINLRTGPEWTRCIQAVSQNKNIFPSLTNVSEVVTDQFLCSGMEEEDDNPCKGESGGAVFLGRRYRFFQVGLVSWGLFDPCHGSSNKNLRKKPPRGVLPRDFHISLFRLQPWLRQHLDGVLDFLPL
Sequence Length
742
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,013 Da
NCBI Official Full Name
complement C2 preproprotein
NCBI Official Synonym Full Names
complement component 2 (within H-2S)
NCBI Official Symbol
C2
NCBI Protein Information
complement C2
UniProt Protein Name
Complement C2
Protein Family
UniProt Gene Name
C2
NCBI Description
This gene encodes component C2 of the classical pathway of the complement system. The encoded protein undergoes proteolytic processing mediated by component C1 resulting in C2a and C2b fragments. C2a fragment, in turn, selectively cleaves components C3 and C5 of the complement system. Mice lacking the encoded protein are found to be more susceptible to bacterial infections. Mutations in the human homolog of this gene are associated with disorders such as systemic lupus erythematosus, Henoch-Schonlein purpura, or polymyositis. [provided by RefSeq, Mar 2015]
Uniprot Description
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
Research Articles on C2
Similar Products
Product Notes
The C2 c2 (Catalog #AAA964399) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-760, Full length protein. The amino acid sequence is listed below: ALFCNQNVNI TGGNFTLSHG WAPGSLLIYS CPLGRYPSPA WRKCQSNGQW LTPRSSSHHT LRSSRMVKAV CKPVRCLAPS SFENGIYFPR LVSYPVGSNV SFECEQDFTL RGSPVRYCRP NGLWDGETAV CDNGASHCPN PGISVGTART GLNFDLGDKV RYRCSSSNMV LTGSAERECQ SNGVWSGSEP ICRQPYSYDF PEDVASALDT SLTNLLGATN PTQNLLTKSL GRKIIIQRSG HLNLYLLLDA SQSVTEKDFD IFKKSAELMV ERIFSFEVNV SVAIITFASQ PKTIMSILSE RSQDVTEVIT SLDSASYKDH ENATGTNTYE VLIRVYSMMQ SQMDRLGMET SAWKEIRHTI ILLTDGKSNM GDSPKKAVTR IRELLSIEQN RDDYLDIYAI GVGKLDVDWK ELNELGSKKD GERHAFILQD AKALQQIFEH MLDVSKLTDT ICGVGNMSAN ASDQERTPWQ VTFKPKSKET CQGSLISDQW VLTAAHCFHD IQMEDHHLWR VNVGDPTSQH GKEFLVEDVI IAPGFNVHAK RKQGISEFYA DDIALLKLSR KVKMSTHARP ICLPCTVGAN MALRRSPGST CKDHETELLS QQKVPAHFVA LNGNRLNINL RTGPEWTRCI QAVSQNKNIF PSLTNVSEVV TDQFLCSGME EEDDNPCKGE SGGAVFLGRR YRFFQVGLVS WGLFDPCHGS SNKNLRKKPP RGVLPRDFHI SLFRLQPWLR QHLDGVLDFL PL. It is sometimes possible for the material contained within the vial of "Complement C2 (C2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
