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Western Blot (WB) (Western blot analysis of ACOX2 using HuvEc whole cell lysates)

Rabbit ACOX2 Polyclonal Antibody | anti-ACOX2 antibody

ACOX2 Antibody

Gene Names
ACOX2; BCOX; BRCOX; CBAS6; THCCox; BRCACOX
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ACOX2; Polyclonal Antibody; ACOX2 Antibody; 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; 3 alpha 7 alpha 12 alpha trihydroxy 5 beta cholestanoyl CoA oxidase; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholestanoyl CoA 24 hydroxylase; 3-alpha; 7-alpha; ACOX 2; ACOX2_HUMAN; Acyl CoA oxidase 2; Acyl Coenzyme A oxidase 2; Acyl Coenzyme A oxidase 2 branched chain; Acyl coenzyme A oxidase 2 peroxisomal; BCOX; BRCACOX; BRCOX; Peroxisomal acyl-coenzyme A oxidase 2; Peroxisomal branched chain acyl CoA oxidase; THCA CoA oxidase; THCA-CoA oxidase; THCCox; Trihydroxycoprostanoyl CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase; anti-ACOX2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ACOX2 antibody detects endogenous levels of total ACOX2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
681
Applicable Applications for anti-ACOX2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human ACOX2
Subcellular Location
Peroxisome.
Tissue Specificity
Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
Predicted Cross Reactivity
Bovine, Sheep, Rabbit, Dog
Similarity
Bovine (100%), Sheep (100%), Rabbit (90%), Dog (80%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of ACOX2 using HuvEc whole cell lysates)

Western Blot (WB) (Western blot analysis of ACOX2 using HuvEc whole cell lysates)
Related Product Information for anti-ACOX2 antibody
Function: Oxidizes the CoA esters of the bile acid intermediates di-and tri-hydroxycholestanoic acids.
Subunit Structure: Homodimer.
Similarity: Belongs to the acyl-CoA oxidase family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 77 kDa
Predicted: 77 kDa
NCBI Official Full Name
peroxisomal acyl-coenzyme A oxidase 2
NCBI Official Synonym Full Names
acyl-CoA oxidase 2
NCBI Official Symbol
ACOX2
NCBI Official Synonym Symbols
BCOX; BRCOX; CBAS6; THCCox; BRCACOX
NCBI Protein Information
peroxisomal acyl-coenzyme A oxidase 2
UniProt Protein Name
Peroxisomal acyl-coenzyme A oxidase 2
UniProt Gene Name
ACOX2
UniProt Synonym Gene Names
THCA-CoA oxidaseBy similarityManual assertion inferred from sequence similarity toiUniProtKB:O02767 (ACOX2_RABIT); THCCox

NCBI Description

The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. [provided by RefSeq, Mar 2009]

Uniprot Description

Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids.

Research Articles on ACOX2

Similar Products

Product Notes

The ACOX2 acox2 (Catalog #AAA9609471) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACOX2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ACOX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the ACOX2 acox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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