Rabbit anti-Human, Mouse ACOX2 Polyclonal Antibody | anti-ACOX2 antibody

ACOX2 (Acyl-Coenzyme A Oxidase 2, Branched Chain, BCOX, BRCACOX, BRCOX, THCCox, Peroxisomal Branched Chain Acyl-CoA Oxidase, THCA-CoA Oxidase, Trihydroxycoprostanoyl-CoA Oxidase) (Biotin)

Cat. Num. AAA6368573

• Gene Names: ACOX2; BCOX; BRCOX; THCCox; BRCACOX
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ACOX2; Polyclonal Antibody; ACOX2 (Acyl-Coenzyme A Oxidase 2; Branched Chain; BCOX; BRCACOX; BRCOX; THCCox; Peroxisomal Branched Chain Acyl-CoA Oxidase; THCA-CoA Oxidase; Trihydroxycoprostanoyl-CoA Oxidase) (Biotin); anti-ACOX2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ACOX2. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-ACOX2 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human ACOX2, aa1-681 (NP_003491.1).
• Immunogen Sequence: MGSPVHRVSLGDTWSRQMHPDIESERYMQSFDVERLTNILDGGAQNTALRRKVESIIHSYPEFSCKDNYFMTQNERYKAAMRRAFHIRLIARRLGWLEDGRELGYAYRALSGDVALNIHRVFVRALRSLGSEEQIAKWDPLCKNIQIIATYAQTELGHGTYLQGLETEATYDAATQEFVIHSPTLTATKWWPGDLGRSATHALVQAQLICSGARRGMHAFIVPIRSLQDHTPLPGIIIGDIGPKMDFDQTDNGFLQLNHVRVPRENMLSRFAQVLPDGTYVKLGTAQSNYLPMVVVRVELLSGEILPILQKACVIAMRYSVIRRQSRLRPSDPEAKVLDYQTQQQKLFPQLAISYAFHFLAVSLLEFFQHSYTAILNQDFSFLPELHALSTGMKAMMSEFCTQGAEMCRRACGGHGYSKLSGLPSLVTKLSASCTYEGENTVLYLQVARFLVKSYLQTQMSPGSTPQRSLSPSVAYLTAPDLARCPAQRAADFLCPELYTTAWAHVAVRLIKDSVQHLQTLTQSGADQHEAWNQTTVIHLQAAKVHCYYVTVKGFTEALEKLENEPAIQQVLKRLCDLHAIHGILTNSGDFLHDAFLSGAQVDMARTAYLDLLRLIRKDAILLTDAFDFTDQCLNSALGCYDGNVYERLFQWAQKSPTNTQENPAYEEYIRPLLQSWRSKL
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ACOX2 rabbit polyclonal antibody. Western Blot analysis of ACOX2 expression in mouse liver)

Western Blot (WB)

(Western Blot analysis of ACOX2 expression in transfected 293T cell line by ACOX2 polyclonal antibody. Lane 1: ACOX2 transfected lysate (76.8kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ACOX2 antibody

ACOX2 belongs to the acyl-CoA oxidases family. It is a branched-chain acyl-CoA oxidase, and is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. It oxidizes the CoA esters of the bile acid intermediates di-and tri-hydroxycholestanoic acids. Mutations resulting in the deficiency of ACOX2 lead to the accumulation of branched fatty acids and bile acid intermediates.

Product Categories/Family for anti-ACOX2 antibody

Antibodies; Enzymes; Oxidase

NCBI and Uniprot Product Information

• NCBI GI #: 4501869
• NCBI GeneID: 8309
• NCBI Accession #: NP_003491.1
• NCBI GenBank Nucleotide #: NM_003500.2
• Molecular Weight: 76,827 Da
• NCBI Official Full Name: peroxisomal acyl-coenzyme A oxidase 2
• NCBI Official Synonym Full Names: acyl-CoA oxidase 2, branched chain
• NCBI Official Symbol: ACOX2
• NCBI Official Synonym Symbols: BCOX; BRCOX; THCCox; BRCACOX
• NCBI Protein Information: peroxisomal acyl-coenzyme A oxidase 2
• Protein Family: Peroxisomal acyl-coenzyme A oxidase

NCBI Description

The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009]