Western Blot (WB)
(ACOX2 Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ACOX2 antibody detected the ACOX2 protein (arrow).)
Rabbit anti-Human ACOX2 Polyclonal Antibody | anti-ACOX2 antibody
ACOX2 Antibody (N-term)
Western Blot (WB)
(ACOX2 Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ACOX2 antibody detected the ACOX2 protein (arrow).)
Western Blot (WB)
(ACOX2 Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the ACOX2 antibody detected the ACOX2 protein (arrow).)
family. It encodes the branched-chain acyl-CoA oxidase which is
involved in the degradation of long branched fatty acids and bile
acid intermediates in peroxisomes. Deficiency of this enzyme
results in the accumulation of branched fatty acids and bile acid
intermediates, and may lead to Zellweger syndrome, severe mental
retardation, and death in children.
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Wanders, R.J., et al. Annu. Rev. Biochem. 75, 295-332 (2006) :
Moghrabi, N.N., et al. Biochem. Biophys. Res. Commun. 231(3):767-769(1997)
Baumgart, E., et al. Ann. N. Y. Acad. Sci. 804, 678-679 (1996) :
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009]
Uniprot Description
ACOX2: Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Belongs to the acyl-CoA oxidase family.
Protein type: Oxidoreductase; Lipid Metabolism - primary bile acid biosynthesis; EC 1.17.99.3
Chromosomal Location of Human Ortholog: 3p14.3
Cellular Component: peroxisomal matrix; peroxisome
Molecular Function: acyl-CoA dehydrogenase activity; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity; acyl-CoA oxidase activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding
Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation using acyl-CoA oxidase; bile acid metabolic process; cellular lipid metabolic process
Research Articles on ACOX2
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Product Notes
The ACOX2 acox2 (Catalog #AAA9213172) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The ACOX2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACOX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ACOX2 acox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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