Mouse KC ELISA Kit | KC elisa kit

KC (Murine) OmniKine ELISA Kit

Cat. Num. AAA9501916

• Gene Names: Cxcl1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1
• Reactivity: Mouse
• Synonyms: KC; KC (Murine) OmniKine ELISA Kit; Growth-regulated alpha protein; C-X-C motif chemokine 1; Platelet-derived growth factor-inducible protein KC; Secretory protein N51; KC elisa kit

• Reactivity: Mouse
• Specificity: The OmniKine Murine KC ELISA is capable of recognizing both recombinant and naturally produced Murine KC proteins. The antigens listed below were tested at 50 ng/ml and exhibited less than 1% cross reactivity.; Rat: GROalpha; The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.; Human: ENA-78, GCP-2, GROalpha, GRObeta, GROgamma, IL-8, NAP-2; Murine: IL-13; Rat: GRObeta
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 96

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 8-1000 pg/ml
• Sensitivity: 8-1000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Murine KC ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine KC proteins within the range of 8-1000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 6680109
• NCBI GeneID: 14825
• NCBI Accession #: NP_032202.1
• NCBI GenBank Nucleotide #: NM_008176.3
• UniProt Accession #: P12850
• Molecular Weight: 10,254 Da
• NCBI Official Full Name: growth-regulated alpha protein
• NCBI Official Synonym Full Names: chemokine (C-X-C motif) ligand 1
• NCBI Official Symbol: Cxcl1
• NCBI Official Synonym Symbols: KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1
• NCBI Protein Information: growth-regulated alpha protein
• UniProt Protein Name: Growth-regulated alpha protein
• Protein Family: KCNQ1 downstream neighbor protein
• UniProt Gene Name: Cxcl1
• UniProt Synonym Gene Names: Gro; Gro1; Mgsa; Scyb1; HSF

NCBI Description

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]

Uniprot Description

CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5 E1|5 44.78 cM

Cellular Component: extracellular region; extracellular space

Molecular Function: chemokine activity; CXCR chemokine receptor binding; cytokine activity; growth factor activity

Biological Process: acute inflammatory response; chemotaxis; defense response; elevation of cytosolic calcium ion concentration; G-protein coupled receptor signaling pathway; immune response; inflammatory response; neutrophil chemotaxis; positive regulation of potassium ion transport; positive regulation of superoxide anion generation; response to lipopolysaccharide; response to molecule of bacterial origin