Western Blot (WB)
(UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).)
Rabbit anti-Human UNC5D Polyclonal Antibody | anti-UNC5D antibody
UNC5D Antibody (Center)
Gene Names
UNC5D; Unc5h4; PRO34692
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
UNC5D; Polyclonal Antibody; UNC5D Antibody (Center); Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D; KIAA1777; UNC5H4; anti-UNC5D antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-511 amino acids from the Central region of human UNC5D.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
483-511
Sequence Length
948
Applicable Applications for anti-UNC5D antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).)
Western Blot (WB)
(UNC5D Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UNC5D antibody detected the UNC5D protein (arrow).)
Related Product Information for anti-UNC5D antibody
UNC5D is receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
Product Categories/Family for anti-UNC5D antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Wang, H., et al. Biochem. Biophys. Res. Commun. 370(4):594-598(2008)
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
Zhong, Y., et al. Cereb. Cortex 14(10):1144-1152(2004)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Wang, H., et al. Biochem. Biophys. Res. Commun. 370(4):594-598(2008)
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
Zhong, Y., et al. Cereb. Cortex 14(10):1144-1152(2004)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
105880
NCBI Official Full Name
netrin receptor UNC5D
NCBI Official Synonym Full Names
unc-5 netrin receptor D
NCBI Official Symbol
UNC5D
NCBI Official Synonym Symbols
Unc5h4; PRO34692
NCBI Protein Information
netrin receptor UNC5D
UniProt Protein Name
Netrin receptor UNC5D
Protein Family
UniProt Gene Name
UNC5D
UniProt Synonym Gene Names
KIAA1777; UNC5H4
UniProt Entry Name
UNC5D_HUMAN
Uniprot Description
UNC5D: Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Belongs to the unc-5 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 8p12
Cellular Component: cell surface; integral to membrane
Biological Process: axon guidance; pyramidal neuron differentiation; apoptosis; signal transduction
Research Articles on UNC5D
Similar Products
Product Notes
The UNC5D unc5d (Catalog #AAA9203437) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 483-511. The UNC5D Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UNC5D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the UNC5D unc5d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UNC5D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
