Western Blot (WB)
(AKIRIN2 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the AKIRIN2 antibody detected the AKIRIN2 protein (arrow).)
Rabbit AKIRIN2 Polyclonal Antibody | anti-AKIRIN2 antibody
AKIRIN2 Antibody (C-term)
Western Blot (WB)
(AKIRIN2 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the AKIRIN2 antibody detected the AKIRIN2 protein (arrow).)
Western Blot (WB)
(AKIRIN2 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the AKIRIN2 antibody detected the AKIRIN2 protein (arrow).)
Western Blot (WB)
(Western blot analysis of AKIRIN2 (arrow) using rabbit polyclonal AKIRIN2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AKIRIN2 gene.)
Western Blot (WB)
(Western blot analysis of AKIRIN2 (arrow) using rabbit polyclonal AKIRIN2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AKIRIN2 gene.)
Goto, A., et al. Nat. Immunol. 9(1):97-104(2008)
Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :
Vasan, R.S., et al. BMC Med. Genet. 8 SUPPL 1, S2 (2007) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
NCBI and Uniprot Product Information
Uniprot Description
AKIRIN2: Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1. Belongs to the akirin family.
Protein type: Cell cycle regulation; Transcription regulation
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: transcriptional repressor complex; nucleus
Molecular Function: enzyme binding
Biological Process: embryonic development; transcription, DNA-dependent; positive regulation of cell proliferation; innate immune response; positive regulation of interleukin-6 production; positive regulation of transcription from RNA polymerase II promoter; response to lipopolysaccharide; negative regulation of transcription from RNA polymerase II promoter
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Product Notes
The AKIRIN2 akirin2 (Catalog #AAA9210163) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 177-203. The AKIRIN2 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's AKIRIN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AKIRIN2 akirin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKIRIN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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