Mouse macrophage stimulating 1 receptor (c-met-related tyrosine kinase) ELISA Kit | MST1R elisa kit
Mouse Macrophage-stimulating protein receptor, MST1R ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a precursor protein that is proteolytically cleaved to yield an alpha chain and a beta chain which form a membrane-spanning heterodimer. The encoded protein belongs to a family of cell-surface receptor tyrosine kinases involved in signaling from the cell surface to the intracellular environment. The binding of the encoded protein to its ligand, macrophage-stimulating protein, mediates several biological activities including wound healing, tumor immunity, macrophage activation and hematopoiesis as well as cell growth, motility, survival and adhesion. The protein encoded by this gene also functions in early development and the macrophage-mediated inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
Ron: a receptor tyrosine kinase of the Met family. Receptor for macrophage stimulating protein. Can be desensitized by c-Cbl and its binding partner Grb2. Overexpression of wild-type RON causes the formation of lung tumors. Two alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; EC 2.7.10.1; Kinase, protein; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Met family
Cellular Component: cell surface; membrane; plasma membrane; stress fiber; integral to membrane
Molecular Function: transferase activity; enzyme binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; ATP binding; protein kinase activity
Biological Process: positive regulation of protein kinase B signaling cascade; positive regulation of MAP kinase activity; viral reproduction; immune system process; multicellular organismal development; response to virus; innate immune response; protein amino acid phosphorylation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on MST1R
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Product Notes
The Mouse MST1R mst1r (Catalog #AAA9341985) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9341985 ELISA Kit recognizes Mouse MST1R. It is sometimes possible for the material contained within the vial of "macrophage stimulating 1 receptor (c-met-related tyrosine kinase), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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