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Macrophage Stimulating 1 Receptor (MST1R) Recombinant Protein | MST1R recombinant protein
Recombinant Macrophage Stimulating 1 Receptor (MST1R)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- IE NLTTGPIGNP GCQTCASCGP GPHGPPKDTD TLVLVMEPGL PALVSCGSTL QGRCFLHELE PRGKALHLAA PACLFSANNN KPEACTDCVA SPLGTRVTVV EQGHASYFYV ASSLDPELAA SFSPRSVSIR RLKSDTSGFQPGFPSLSVLP KYLASYLIKY VYSFHSGDFV YFLTVQPISV TSPPS
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
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NCBI and Uniprot Product Information
NCBI Description
This gene encodes a precursor protein that is proteolytically cleaved to yield an alpha chain and a beta chain which form a membrane-spanning heterodimer. The encoded protein belongs to a family of cell-surface receptor tyrosine kinases involved in signaling from the cell surface to the intracellular environment. The binding of the encoded protein to its ligand, macrophage-stimulating protein, mediates several biological activities including wound healing, tumor immunity, macrophage activation and hematopoiesis as well as cell growth, motility, survival and adhesion. The protein encoded by this gene also functions in early development and the macrophage-mediated inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
Ron: a receptor tyrosine kinase of the Met family. Receptor for macrophage stimulating protein. Can be desensitized by c-Cbl and its binding partner Grb2. Overexpression of wild-type RON causes the formation of lung tumors. Two alternatively spliced isoforms have been described.
Protein type: Kinase, protein; Membrane protein, integral; EC 2.7.10.1; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group; Met family
Cellular Component: cell surface; membrane; integral to membrane; plasma membrane; stress fiber
Molecular Function: transferase activity; enzyme binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; receptor activity; kinase activity; transmembrane receptor protein tyrosine kinase activity; ATP binding; protein kinase activity
Biological Process: positive regulation of protein kinase B signaling cascade; positive regulation of MAP kinase activity; viral reproduction; immune system process; multicellular organismal development; response to virus; innate immune response; protein amino acid phosphorylation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on MST1R
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Product Notes
The MST1R mst1r (Catalog #AAA2018734) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Macrophage Stimulating 1 Receptor (MST1R) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the MST1R mst1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- IE NLTTGPIGNP GCQTCASCGP GPHGPPKDTD TLVLVMEPGL PALVSCGSTL QGRCFLHELE PRGKALHLAA PACLFSANNN KPEACTDCVA SPLGTRVTVV EQGHASYFYV ASSLDPELAA SFSPRSVSIR RLKSDTSGFQ PGFPSLSVLP KYLASYLIKY VYSFHSGDFV YFLTVQPISV TSPPS. It is sometimes possible for the material contained within the vial of "Macrophage Stimulating 1 Receptor (MST1R), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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