CWC22 blocking peptide
CWC22 Antibody (N-term) Blocking peptide
Gene Names
CWC22; NCM; fSAPb; EIF4GL
Synonyms
CWC22; CWC22 Antibody (N-term) Blocking peptide; Pre-mRNA-splicing factor CWC22 homolog; Nucampholin homolog; fSAPb; KIAA1604; NCM; CWC22 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
908
Cellular Location
Nucleus. Nucleus speckle. Note: Concentrates around speckles, which are sites of pre-mRNA synthesis and processing, where it colocalizes with EJC core proteins
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for CWC22 blocking peptide
Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
105,466 Da
NCBI Official Full Name
Pre-mRNA-splicing factor CWC22 homolog
NCBI Official Synonym Full Names
CWC22 homolog, spliceosome-associated protein
NCBI Official Symbol
CWC22
NCBI Official Synonym Symbols
NCM; fSAPb; EIF4GL
NCBI Protein Information
pre-mRNA-splicing factor CWC22 homolog
UniProt Protein Name
Pre-mRNA-splicing factor CWC22 homolog
Protein Family
UniProt Gene Name
CWC22
UniProt Synonym Gene Names
KIAA1604; NCM
UniProt Entry Name
CWC22_HUMAN
Uniprot Description
NCM: a component of the spliceosome C complex.
Protein type: RNA processing; RNA splicing; Spliceosome
Chromosomal Location of Human Ortholog: 2q31.3
Cellular Component: cytoplasm; Golgi apparatus; nuclear speck; nucleoplasm; spliceosome
Molecular Function: protein binding; RNA binding
Biological Process: nuclear mRNA splicing, via spliceosome; regulation of nuclear mRNA splicing, via spliceosome
Research Articles on CWC22
Similar Products
Product Notes
The CWC22 cwc22 (Catalog #AAA9217876) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CWC22, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
