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5HT3E Blocking Peptide | HTR3E blocking peptide

5HT3E Antibody (Center) Blocking Peptide

Gene Names
HTR3E; 5-HT3E; 5-HT3-E; 5-HT3c1
Synonyms
5HT3E; 5HT3E Antibody (Center) Blocking Peptide; 5-hydroxytryptamine receptor 3E; 5-HT3-E; 5-HT3E; Serotonin receptor 3E; HTR3E; HTR3E blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
471
Cellular Location
Cell membrane; Multi-pass membrane protein Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A
Tissue Location
Expressed in adult colon and intestine.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for HTR3E blocking peptide
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,700 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 3E isoform a
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 3E
NCBI Official Symbol
HTR3E
NCBI Official Synonym Symbols
5-HT3E; 5-HT3-E; 5-HT3c1
NCBI Protein Information
5-hydroxytryptamine receptor 3E
UniProt Protein Name
5-hydroxytryptamine receptor 3E
UniProt Gene Name
HTR3E
UniProt Synonym Gene Names
5-HT3-E; 5-HT3E
UniProt Entry Name
5HT3E_HUMAN

NCBI Description

This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012]

Uniprot Description

5-HT(3E): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3E sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, cation; Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 3q27.1

Cellular Component: nicotinic acetylcholine-gated receptor-channel complex; plasma membrane

Molecular Function: acetylcholine binding; acetylcholine receptor activity; nicotinic acetylcholine-activated cation-selective channel activity; serotonin receptor activity; serotonin-activated cation-selective channel activity

Biological Process: synaptic transmission, cholinergic

Research Articles on HTR3E

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Product Notes

The HTR3E htr3e (Catalog #AAA9217667) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "5HT3E, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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