Western Blot (WB)
(Mouse Prkcb Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkcb antibody detected the Prkcb protein (arrow).)
Rabbit Prkcb Polyclonal Antibody | anti-Prkcb antibody
Mouse Prkcb Antibody (N-term)
Western Blot (WB)
(Mouse Prkcb Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkcb antibody detected the Prkcb protein (arrow).)
Western Blot (WB)
(Mouse Prkcb Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkcb antibody detected the Prkcb protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Prkcb Antibody (N-term) (MBS9204823)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Prkcb Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Prkcb Antibody (N-term) (MBS9204823)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Prkcb Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Deng, P.Y., et al. J. Neurosci. 30(15):5136-5148(2010)
Hennige, A.M., et al. J. Cell. Mol. Med. 14(4):903-913(2010)
Kim, Y.A., et al. Neurosci. Lett. 468(3):254-258(2010)
Kleiman, E., et al. Biochem. Biophys. Res. Commun. 388(3):554-559(2009)
NCBI and Uniprot Product Information
Uniprot Description
PKCB iso2: an AGC kinase of the PKC family. A classical PKC downstream of many mitogenic receptors. Activates the NF-kappaB signaling pathway in B cells after antigen-receptor signaling. Two splice-variant isoforms have been described.
Protein type: Protein kinase, AGC; Kinase, protein; EC 2.7.11.13; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; AGC group; PKC family; Alpha subfamily
Cellular Component: centrosome; membrane; brush border membrane; cytoplasm; plasma membrane; cytosol; nucleus
Molecular Function: protein kinase C activity; zinc ion binding; histone binding; metal ion binding; calcium channel regulator activity; nucleotide binding; protein kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; ligand-dependent nuclear receptor transcription coactivator activity; androgen receptor binding; protein kinase C binding; transferase activity, transferring phosphorus-containing groups; kinase activity; chromatin binding; ATP binding
Biological Process: response to drug; positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; B cell activation; apoptosis; immune system process; positive regulation of B cell receptor signaling pathway; negative regulation of insulin receptor signaling pathway; chromatin modification; regulation of dopamine secretion; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; activation of NF-kappaB transcription factor; regulation of transcription from RNA polymerase II promoter; cellular calcium ion homeostasis; positive regulation of angiogenesis; B cell receptor signaling pathway; regulation of transcription, DNA-dependent; calcium ion transport; regulation of growth; response to hypoxia; phosphorylation
Research Articles on Prkcb
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Product Notes
The Prkcb prkcb (Catalog #AAA9204823) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The Mouse Prkcb Antibody (N-term) reacts with Mouse (Predicted Reactivity: Bovine, Human, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Prkcb can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Prkcb prkcb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prkcb, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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