Western Blot (WB)
(Western blot analysis using MBS6007189 at 1:2'000 dilution. 1: Human Progranulin (DYKDDDDK-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (DYKDDDDK-tagged) (50ng). 4: Human Granulin F (DYKDDDDK-tagged) (50ng). 5: Mouse Progranulin (DYKDDDDK-tagged) (50ng). 6: Unrelated Protein (DYKDDDDK-tagged).)
Guinea pig Progranulin Polyclonal Antibody | anti-granulin antibody
Progranulin (Proepithelin, PEPI, PC Cell-derived Growth Factor)
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
Progranulin; Polyclonal Antibody; Progranulin (Proepithelin; PEPI; PC Cell-derived Growth Factor); Anti -Progranulin (Proepithelin; anti-granulin antibody
Host
Guinea pig
Clonality
Polyclonal
Specificity
Recognizes human progranulin. Detects a band of ~90kD by Western blot. Weakly cross-reacts with mouse progranulin. Cross-reacts with hGRN-C and hGRN-F.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.
Applicable Applications for anti-granulin antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA, Western Blot
Immunogen
Recombinant human progranulin.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western blot analysis using MBS6007189 at 1:2'000 dilution. 1: Human Progranulin (DYKDDDDK-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (DYKDDDDK-tagged) (50ng). 4: Human Granulin F (DYKDDDDK-tagged) (50ng). 5: Mouse Progranulin (DYKDDDDK-tagged) (50ng). 6: Unrelated Protein (DYKDDDDK-tagged).)
Western Blot (WB)
(Western blot analysis using MBS6007189 at 1:2'000 dilution. 1: Human Progranulin (DYKDDDDK-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (DYKDDDDK-tagged) (50ng). 4: Human Granulin F (DYKDDDDK-tagged) (50ng). 5: Mouse Progranulin (DYKDDDDK-tagged) (50ng). 6: Unrelated Protein (DYKDDDDK-tagged).)
Immunohistochemistry (IHC)
(Immunohistochemical staining of progranulin using MBS6007189 in formalin-fixed and paraffin-embedded (FFPE) human pancreas tissue (10ug/ml).)
Immunohistochemistry (IHC)
(Immunohistochemical staining of progranulin using MBS6007189 in formalin-fixed and paraffin-embedded (FFPE) human pancreas tissue (10ug/ml).)
Related Product Information for anti-granulin antibody
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer's Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
Product Categories/Family for anti-granulin antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
progranulin
NCBI Official Symbol
granulin
NCBI Protein Information
progranulin
Similar Products
Product Notes
The granulin (Catalog #AAA6007189) is an Antibody produced from Guinea pig and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Progranulin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA, Western Blot. Researchers should empirically determine the suitability of the granulin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Progranulin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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