Mouse anti-Human PTPDC1 Polyclonal Antibody | anti-Ptpdc1 antibody

PTPDC1 (Protein Tyrosine Phosphatase Domain-containing Protein 1, PTP9Q22)

Cat. Num. AAA6002775

• Gene Names: Ptpdc1; Naa-1; AI843923; AW456874
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: PTPDC1; Polyclonal Antibody; PTPDC1 (Protein Tyrosine Phosphatase Domain-containing Protein 1; PTP9Q22); Anti -PTPDC1 (Protein Tyrosine Phosphatase Domain-containing Protein 1; anti-Ptpdc1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PTPDC1.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MAAGVLPQNEQPYSTLVNNSECVANMKGNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCDPKAHAVTLPQYLIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMKDVSEGPGLSAEIEKTMSEMVTMQLDKELLRHDSDFSNPPNPTAVAADFDNRGMIFSNEQQFDPLWKRRNVECLQPLTHLKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQKLISHCYIPQSPEPDLHKEALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSGAFSADVSGSHSPGEPVSPSFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSPLDCGSSPKAQFLVEHETQDSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEELKRKVEMWQKELNSRDGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRADAAEALFLLEKGQHQTILCVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVYNTLKKIFKHTLEEKRKMTKDGPKPGL

• Applicable Applications for anti-Ptpdc1 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human PTPDC1, aa1-754 (AAH67120.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of PTPDC1 expression in transfected 293T cell line by PTPDC1 polyclonal antibody. Lane 1: PTPDC1 transfected lysate (82.94kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-Ptpdc1 antibody

Antibodies; Abs to Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 46189233
• NCBI GeneID: 218232
• UniProt Accession #: Q6NZK8; Q3V0Z6; Q3V3K9; Q3V3Y0; Q6NV81; Q8BKD9
• Molecular Weight: 83,934 Da
• NCBI Official Full Name: Ptpdc1 protein
• NCBI Official Synonym Full Names: protein tyrosine phosphatase domain containing 1
• NCBI Official Symbol: Ptpdc1
• NCBI Official Synonym Symbols: Naa-1; AI843923; AW456874
• NCBI Protein Information: protein tyrosine phosphatase domain-containing protein 1
• UniProt Protein Name: Protein tyrosine phosphatase domain-containing protein 1
• Protein Family: Protein tyrosine phosphatase domain-containing protein
• UniProt Gene Name: Ptpdc1
• UniProt Entry Name: PTPC1_MOUSE

NCBI Description

The protein encoded by this gene is a centrosomal mitotic phosphatase. This protein has been implicated in centrosomal duplication and cytokinesis. In addition, knockdown of expression levels in non-cycling cells results in extra long cilia, suggesting that this protein may function in regulating cilia length independent of a function in cell cycle control. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

Uniprot Description

PTPDC1: May play roles in cilia formation and/or maintenance. Belongs to the protein-tyrosine phosphatase family. Non-receptor class PTPDC1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.-; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)

Cellular Component: nucleoplasm

Molecular Function: protein tyrosine/threonine phosphatase activity; inositol-1,3,4-trisphosphate 4-phosphatase activity; hydrolase activity; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; protein tyrosine phosphatase activity; inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity; inositol bisphosphate phosphatase activity; inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; JUN kinase phosphatase activity; transmembrane receptor protein phosphatase activity; NADP phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity; phosphoric monoester hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; inositol-4,5-bisphosphate 5-phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphohistidine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: smoothened signaling pathway; dephosphorylation; cell projection organization and biogenesis; protein amino acid dephosphorylation