Panaxynol, Inhibitor
Panaxynol
Purity
98.00%
Synonyms
Panaxynol; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C17H24O
SMILES
CCCCCCC/C=C\CC#CC#C[C@H](C=C)O
CAS Number
81203-57-8
Target & IC50
Bcl-2
Caspase
HIF
Caspase
HIF
In Vitro
Panaxynol (0.1mg/ml) inhibited markedly the aggregation of washed platelets induced by collagen, arachidonic acid, ADP, ionophore A23187, PAF and thrombin while ginsenosides had no significant effect on the aggregation but ginsenoside Ro (1mg/ml) inhibited the ATP release of platelets. Less inhibitory effect of Panaxynol was observed in the aggregation of platelet-rich plasma. Thromboxane B2 formation of platelets was inhibited by Panaxynol but not by ginsenosides. The antiplatelet effect of Panaxynol was dependent on the incubation time and the aggregability of platelets inhibited by Panaxynol could not easily be recovered after washing the platelets. In human platelet-rich plasma, Panaxynol prevented secondary aggregation and completely blocked ATP release from platelets induced by epinephrine and ADP. Both Panaxynol and ginsenoside Rg2 inhibited the rise of intracellular calcium caused by collagen[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Panaxynol, inhibitor
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation.
Product Categories/Family for Panaxynol, inhibitor
References
Antiplatelet actions of panaxynol and ginsenosides isolated from ginseng. Biochim Biophys Acta. 1989 Mar 24;990(3):315-20.
Antiplatelet actions of panaxynol and ginsenosides isolated from ginseng. Biochim Biophys Acta. 1989 Mar 24;990(3):315-20.
Panaxynol induces neurite outgrowth in PC12D cells via cAMP- and MAP kinase-dependent mechanisms.Chem Biol Interact. 2006 Jan 5;159(1):58-64.
Antiplatelet actions of panaxynol and ginsenosides isolated from ginseng. Biochim Biophys Acta. 1989 Mar 24;990(3):315-20.
Panaxynol induces neurite outgrowth in PC12D cells via cAMP- and MAP kinase-dependent mechanisms.Chem Biol Interact. 2006 Jan 5;159(1):58-64.
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Product Notes
The Panaxynol (Catalog #AAA5760756) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Panaxynol, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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