Immunohistochemistry (IHC)
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Rabbit anti-Human ErbB-2 + HER-2 + Neu Monoclonal Antibody | anti-ErbB-2 + HER-2 + Neu antibody
ErbB-2 + HER-2 + Neu antibody
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
ErbB-2 + HER-2 + Neu; Monoclonal Antibody; ErbB-2 + HER-2 + Neu antibody; Monoclonal ErbB-2 + HER-2 + Neu; Anti-ErbB-2 + HER-2 + Neu; ERBB 2; ERBB -2; ErbB-2 (HER-2/Neu); ERBB2; anti-ErbB-2 + HER-2 + Neu antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
SP3
Specificity
Human
Form/Format
Tissue culture supernatant with 15mM NaN3.
Applicable Applications for anti-ErbB-2 + HER-2 + Neu antibody
Immunohistochemistry (IHC) Formalin/Paraffin
Application Notes
IHC-F: 1:200
IHC-P: 1:200
IHC-P: 1:200
Biological Significance
HER2 gene encodes a transmembrane glycoprotein with tyrosine kinase activity. It is closely related in structure to the epidermal growth factor receptor c-erbB-3/HER3/neu oncoprotein. The protein is detectable in a subset of breast and other carcinomas (urinary bladder, stomach, lung, endometrium and ovary). In the case of breast cancer, over expression determined by immunohistochemistry has been shown to be associated with poor prognosis and an indication to initiate trastuzumab/herceptin therapy.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
ErbB-2/HER-2/Neu antibody was raised in rabbit using recombinant protein encoding extracellular domain of human c-erbB2 as the immunogen.
Preparation and Storage
Store at 4 degree C.
Immunohistochemistry (IHC)
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Immunohistochemistry (IHC)
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Related Product Information for anti-ErbB-2 + HER-2 + Neu antibody
Rabbit monoclonal ErbB-2 + HER-2 + Neu antibody
Product Categories/Family for anti-ErbB-2 + HER-2 + Neu antibody
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Product Notes
The ErbB-2 + HER-2 + Neu (Catalog #AAA531732) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ErbB-2 + HER-2 + Neu antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ErbB-2 + HER-2 + Neu can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Formalin/Paraffin. IHC-F: 1:200 IHC-P: 1:200. Researchers should empirically determine the suitability of the ErbB-2 + HER-2 + Neu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ErbB-2 + HER-2 + Neu, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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