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Dilution Information

Rabbit anti-Human HER2 neu Phospho Monoclonal Antibody | anti-HER2 antibody

HER2 neu Phospho (EP123)

Reactivity
Human
Synonyms
HER2 neu Phospho; Monoclonal Antibody; HER2 neu Phospho (EP123); ERBB2; HER2; phospho Neu; phosphorylated Neu; p- Neu; p Neu; pNeu; anti ERBB2; anti HER2; anti p Neu; anti p-Neu; anti pNeu; anti-ERBB2; anti-HER2; anti-p Neu; anti-p-Neu; anti-pNeu; c erb B2 neu protein; CD340; HER 2; HER 2 neu; herstatin; MLN 19; NEU; neuroblastoma glioblastoma derived oncogene homolog; NGL; p185erbB2; Receptor tyrosine protein kinase erbB 2; TKR1; tyrosine kinase type cell surface receptor HER2; v erb b2 avian erythroblastic leukemia viral oncogene homolog 2 neuro glioblastoma derived oncogene homolog; v erb b2 erythroblastic leukemia viral oncogene homolog 2 neuro glioblastoma derived oncogene homolog avian; Metastatic lymph node gene 19 protein; Proto oncogene c ErbB 2; proto oncogene Neu; anti-HER2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
EP123
Form/Format
Paraffin, Frozen
HER-2 neu phospho antibody is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
A synthetic peptide corresponding to residues surrounding tyrosine 877 of human HER2 protein.
Control
Breast Carcinoma
Localization
Membranous
Preparation and Storage
Store at 2-8 degree C

Dilution Information

Dilution Information

Immunohistochemistry (IHC)

(HER-2 neu Phospho Antibody Immunohistochemistry on a FFPE Breast Carcinoma Tissue)

Immunohistochemistry (IHC) (HER-2 neu Phospho Antibody Immunohistochemistry on a FFPE Breast Carcinoma Tissue)
Related Product Information for anti-HER2 antibody
HER-2 neu Phospho is a rabbit monoclonal antibody for immunohistochemistry from Bio SB. HER2/ErbB2 is one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases.The kinase activity of ErbB2 can be activated without a ligand if it is overexpressed, and by association with other ErbB proteins. Autophosphorylation did not modulate receptor turnover. A Tyr-Phe substitution of ErbB2 Tyr-877 homologous to pp60c-src Tyr-416 did not alter ErbB2 biological and biochemical properties, thus excluding the possibility that phosphorylation of this residue, located in the kinase domain, modulates ErbB2 gp185 catalytic function.
HER-2 neu Phospho Antibody overexpression is seen in 25-30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator. Detection of phosphorylated HER-2 neu Phospho Antibody may aid in predicting breast cancer progression.

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Product Notes

The HER2 (Catalog #AAA370413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HER2 neu Phospho (EP123) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "HER2 neu Phospho, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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