Dilution Information
Mouse anti-Human IL1a Monoclonal Antibody | anti-IL1a antibody
IL1a (BSB-138)
Reactivity
Human
Synonyms
IL1a; Monoclonal Antibody; IL1a (BSB-138); il-1a; il1a; anti-il1a; anti-il-1a; il1a antibody; anti-il-1a antibody; cytokine storm; cytokine storm syndrome; cytokine storm antibody; cytokine storm antibodies; sars-cov-2 receptors; sars cov-2 receptors; covid-19 receptors; sars-cov-2 antibodies sars-cov-2 ihc; sars-cov-2 immunohistochemistry; IL1A; IL-1alpha; IL-1 alpha; IL-1a; IL-1 a; IL 1alpha; IL1alpha; anti-IL-1alpha; anti IL-1alpha; anti-IL1A; anti IL1A; anti-IL 1alpha; anti-IL1alpha; anti IL 1alpha; anti IL1alpha; IL-1F1; Hematopoietin-1; Interleukin-1 alpha; anti-IL-1 alpha; anti IL-1 alpha; anti-IL-1F1; anti IL-1F1; anti-Hematopoietin-1; anti Hematopoietin-1; anti-Interleukin-1 alpha; anti Interleukin-1 alpha; hematopoietin 1; IL 1 alpha; IL 1A; IL1; IL1 ALPHA; IL1F1; interleukin 1 alpha; preinterleukin 1 alpha; pro interleukin 1 alpha; anti-IL1a antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
BSB-138
Form/Format
Paraffin, Frozen
IL-1a is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
IL-1a is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Recombinant protein corresponding to the IL-1? of human origin.
Control
Kidney, Colon, Adrenal gland, Testis, Lung
Localization
Cytoplasmic, Membranous
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(IL-1a Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue)
Immunohistochemistry (IHC)
(IL-1a Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue)
Related Product Information for anti-IL1a antibody
IL-1a is a dual-function cytokine, acting as a transcription factor and a cell-signaling molecule. The 31 kDa precursor form is biologically active in the cytosol and as a membrane protein. IL-1a can be cleaved by calpain into the biologically active 17 kDa mature form that regulates the expression of NFKB, and IFN-y and its effectors. Cancer stem cells use IL-1a to maintain an inflammatory tumor microenvironment, however IL-1a is also used in recruiting and proliferating immune cells as a necrosis alarmin in damaged epithelia. IL-1a induces NFKB and STAT3 signaling that supports cancer stem cell growth. IL-1a is a major cytokine in innate inflammation signaling pathways, and is thus involved in many inflammatory diseases and reactions to oxidative stress.
IL-1a antibody is involved in cancer cell cross-talk and metastasis, and the secretion of cell growth, angiogenesis, and inflammation factors as a Damage-Associated Molecular Pattern. Higher expression of IL-1a has been found in gastric cancer and squamous carcinomas of the head and neck that exhibit distant metastasis. IL-1a has also been associated with tumor de-differentiation and metastasis in breast cancer, and with tumor proliferation and angiogenesis in pancreatic cancer.
IL-1a antibody is involved in cancer cell cross-talk and metastasis, and the secretion of cell growth, angiogenesis, and inflammation factors as a Damage-Associated Molecular Pattern. Higher expression of IL-1a has been found in gastric cancer and squamous carcinomas of the head and neck that exhibit distant metastasis. IL-1a has also been associated with tumor de-differentiation and metastasis in breast cancer, and with tumor proliferation and angiogenesis in pancreatic cancer.
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Product Notes
The IL1a (Catalog #AAA370471) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IL1a (BSB-138) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "IL1a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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